53910-25-1
Pentostatin
CAS: 53910-25-1
Molecular Formula: C11H16N4O4
53910-25-1 - Names and Identifiers
| Name | Pentostatin |
| Synonyms | dcf 2'dcf ci-825 cl67310465 (r)-rahydro Pentostatin co-vidarabine 2'-deoxycoformycin (r)-deoxycoformycin Pentostatin(Deoxycoformycin) (r)-3-(2-deoxy-beta-d-pentofuranosyl)-3,6,7,8-tetrahydroimidazo(4,5-d)(1,3)d (r)-3-(2-deoxy-beta-d-erythro-pento-furanosyl)-3,6,7,8-tetrahydroimidazo[4,5-d (8R)-3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol (8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol (8R)-3-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7,8-dihydro-4H-imidazo[4,5-f][1,3]diazepin-8-ol |
| CAS | 53910-25-1 |
| InChI | InChI=1/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9?/m0/s1 |
53910-25-1 - Physico-chemical Properties
| Molecular Formula | C11H16N4O4 |
| Molar Mass | 268.27 |
| Density | 1.2576 (rough estimate) |
| Melting Point | 154-157?C |
| Boling Point | 411.43°C (rough estimate) |
| Specific Rotation(α) | D25 +76.4° (c = 1 in water); D23 +73.0° (c = 1, pH 7 buffer) |
| Flash Point | 344.5°C |
| Solubility | H2O: soluble10mg/mL, clear |
| Vapor Presure | 1.43E-17mmHg at 25°C |
| Appearance | White solid |
| Color | white to beige |
| pKa | 5.2(at 25℃) |
| Storage Condition | -20°C |
| Sensitive | Sensitive to air and easy to absorb moisture |
| Refractive Index | 1.6081 (estimate) |
| Physical and Chemical Properties | white crystals were obtained from methanol-water, melting point 220-225 °c; Melting point 204-209.5 °c turned black at> 150 °c. UV maximum absorption (water at pH 7):282nm(ε8000);(water at pH 11):283nm(ε7970);(water at pH 2):273NM (initially ε7570), 3143 H later). [Α]D23 76.4 °(C = 1, water);[Α]D23 73.0 °(C = 1,pH 7 buffer). pKa 5.2 in water. |
| Use | It is an adenosine deaminase (ADA) inhibitor. For alpha-interferon treatment ineffective hairy cell leukemia. |
53910-25-1 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Toxicity | LD50 oral in mouse: 227mg/kg |
53910-25-1 - Nature
Open Data Verified Data
white crystals were obtained from methanol and water, with melting points of 220-225 ° C. And melting points of 204-209.5 ° C., which turned black at> 150 ° C., respectively. UV maximum absorption (pH 7 water):282nm(E 8000); (pH 11 water):283nm(E 7970); (Ph 2 water):273nm (initially Δ50, 7570, after 3143 H).
Last Update：2024-01-02 23:10:35
53910-25-1 - Preparation Method
Open Data Verified Data
each was prepared by a fermentation method, and the selected medium was implanted into a water-soluble nutrient solution and incubated under aseptic conditions to obtain pentostatin.
Last Update：2022-01-01 09:09:05
53910-25-1 - Use
Open Data Verified Data
developed by Parke Davis, Inc., launched in 1991. It is an adenosine deaminase (ADA) inhibitor. For hairy cell leukemia in response to alpha-interferon therapy.
Last Update：2022-01-01 09:09:05
Supplier List
Spot supply
Product Name: Pentostatin Visit Supplier Webpage Request for quotationCAS: 53910-25-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Pentostatin Visit Supplier Webpage Request for quotationCAS: 53910-25-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History