54230-60-3

54230-60-3 - Names and Identifiers

Name	1-(2,4,6-triisopropylbenzenesulfonyl)-1H 1,2,4-triazole
Synonyms	TPST 1-Trisyl-1,2,4-triazole 2,4,6-Triisopropylbenzenesulfonyl-1H-1,2,4-triazole 1-(2,4,6-TRIISOPROPYLBENZENESULFONYL)-1,2,4-TRIAZOLE 1-(2,4,6-TRIISOPROPYLBENZENESULPHONYL)-1,2,4-TRIAZOLE 1-(2,4,6-Triisopropylbenzenesulphonyl)-1,2,4-triazole 1-(2,4,6-TRIISOPROPYLPHENYLSULFONYL)-1H-1,2,4-TRIAZOLE 1-(2,4,6-TRIISOPROPYLBENZENESULFONYL)-1H-1,2,4-TRIAZOLE 1-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-1,2,4-triazole 1-(2,4,6-triisopropylbenzenesulfonyl)-1H 1,2,4-triazole 1-[[2,4,6-Tris(isopropyl)phenyl]sulphonyl]-1H-1,2,4-triazole 1-[[2,4,6-tris(isopropyl)phenyl]sulphonyl]-1H-1,2,4-triazole 1-{[2,4,6-tri(propan-2-yl)phenyl]sulfonyl}-1H-1,2,4-triazole
CAS	54230-60-3
EINECS	259-035-7
InChI	InChI=1/C17H25N3O2S/c1-11(2)14-7-15(12(3)4)17(16(8-14)13(5)6)23(21,22)20-10-18-9-19-20/h7-13H,1-6H3

54230-60-3 - Physico-chemical Properties

Molecular Formula	C17H25N3O2S
Molar Mass	335.46
Density	1.17±0.1 g/cm3(Predicted)
Melting Point	111-114°C
Boling Point	451.9±55.0 °C(Predicted)
Flash Point	227.1°C
Vapor Presure	2.34E-08mmHg at 25°C
pKa	-1.13±0.11(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Sensitive	Moisture Sensitive
Refractive Index	1.578
MDL	MFCD00014089

54230-60-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37 - Wear suitable gloves.
WGK Germany	3
FLUKA BRAND F CODES	10-21
HS Code	29339900

54230-60-3 - Introduction

1-(2,4,)-1H 1,2,4-triazole is an organic compound with the chemical formula C18H24N2O2S. The following are the properties, use, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow solid
-melting point: about 130-135 ℃
-Solubility: Soluble in organic solvents such as xylene, acetonitrile and chlorinated methane

Use:
1-(2,4, over)-1H 1,2,4-triazole has a wide range of applications, including:
-Protecting group in chemical synthesis: can be used as a reagent for protecting functional groups such as amine and hydroxyl groups
-Drug Research: Can be used to synthesize new drug molecules
-precursor of catalyst in organic synthesis

Preparation Method:
1-(2,4, 2)-1H 1,2,4-triazole can be prepared by the following steps:
1.2,4,6-triisopropylbenzenesulfonyl chloride (C18H27ClOS) is reacted with 1,2,4-triazole (C2H3N3) to obtain the intermediate of 1-(2,4, 4-triazole)-1H 1,2,4-triazole.
2. Further reaction of the intermediate with alcohol or carbonate can synthesize 1-(2,4,)-1H 1,2,4-triazole.

Safety Information:
1-(2,4, 2)-1H 1,2,4-triazole may have the following safety risks to human body:
-eye and skin irritation. Contact with eyes and skin should be avoided.
-Do not breathe the dust or fumes of this compound.
-Wear appropriate safety equipment such as gloves, goggles and protective clothing during use or handling.

When using this compound, it is necessary to follow relevant safety operating procedures and ensure that it is operated in a well-ventilated environment. In the event of accidental leakage or contact, appropriate first aid and cleaning measures should be taken immediately.

Last Update：2024-04-09 02:00:46