54303-63-8
5-Bromo-2-hydrazino-1H-1,3-benzimidazole
CAS: 54303-63-8
Molecular Formula: C7H7BrN4
54303-63-8 - Names and Identifiers
54303-63-8 - Physico-chemical Properties
| Molecular Formula | C7H7BrN4 |
| Molar Mass | 227.06 |
| Melting Point | 96-98°C |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD08276936 |
54303-63-8 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
54303-63-8 - Introduction
5-Bromo-2-hydrazino-1H-1,3-benzimidazole (5-bromo-2-hydrazino-1H-1, 3-benzimidazole) is an organic compound. Its chemical structure contains a benzimidazole ring and a bromo and hydrazino substituent. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Bromo-2-hydrazino-1H-1,3-benzimidazole is a white solid.
-Melting point: Its melting point is about 250-252 ℃.
-Solubility: Soluble in common solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
- 5-Bromo-2-hydrazino-1H-1,3-benzimidazole has important applications in organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds.
-It is also widely used in the field of drug research and development to design molecular structures related to biological activities.
Preparation Method:
5-Bromo-2-hydrazino-1H-1,3-benzimidazole is usually synthesized by the following steps:
1. Benzimidazole (benzimidazole) reacts with bromoacetate (bromoacetic ester) to generate benzimidazole-2-formate (benzimidazole-2-carboxylic ester).
2. Benzimidazole-2-formate reacts with hydrazine (hydrazine) and condenses under alkaline conditions to generate 5-Bromo-2-hydrazino-1H-1,3-benzimidazole.
Safety Information:
The safety information for 5-Bromo-2-hydrazino-1H-1,3-benzimidazole is not yet reported in detail. However, as an organic compound, it should be regarded as a hazardous substance and care should be taken to follow appropriate safe operating procedures and measures. Wear chemical protective gloves and goggles during handling and use, and ensure that the operation is carried out in a well-ventilated environment. In case of skin contact or inhalation, rinse immediately with water and seek medical help.
Nature:
-Appearance: 5-Bromo-2-hydrazino-1H-1,3-benzimidazole is a white solid.
-Melting point: Its melting point is about 250-252 ℃.
-Solubility: Soluble in common solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
- 5-Bromo-2-hydrazino-1H-1,3-benzimidazole has important applications in organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds.
-It is also widely used in the field of drug research and development to design molecular structures related to biological activities.
Preparation Method:
5-Bromo-2-hydrazino-1H-1,3-benzimidazole is usually synthesized by the following steps:
1. Benzimidazole (benzimidazole) reacts with bromoacetate (bromoacetic ester) to generate benzimidazole-2-formate (benzimidazole-2-carboxylic ester).
2. Benzimidazole-2-formate reacts with hydrazine (hydrazine) and condenses under alkaline conditions to generate 5-Bromo-2-hydrazino-1H-1,3-benzimidazole.
Safety Information:
The safety information for 5-Bromo-2-hydrazino-1H-1,3-benzimidazole is not yet reported in detail. However, as an organic compound, it should be regarded as a hazardous substance and care should be taken to follow appropriate safe operating procedures and measures. Wear chemical protective gloves and goggles during handling and use, and ensure that the operation is carried out in a well-ventilated environment. In case of skin contact or inhalation, rinse immediately with water and seek medical help.
Last Update：2024-04-09 20:45:29
