544678-85-5
MMP-13 Inhibitor
CAS: 544678-85-5
Molecular Formula: C22H20F2N4O2
544678-85-5 - Names and Identifiers
| Name | MMP-13 Inhibitor |
| Synonyms | DB04760 MMP-13 Inhibitor DB04760(DB 04760) DB04760 (COMPOUND 4) N4,N6-Bis(4-fluoro-3-Methylbenzyl)pyriMidine-4,6-dicarboxaMide N,N'-Bis[(4-fluoro-3-methylphenyl)methyl]-4,6-pyrimidinedicarboxamide 4,6-Pyrimidinedicarboxamide, N4,N6-bis[(4-fluoro-3-methylphenyl)methyl]- |
| CAS | 544678-85-5 |
544678-85-5 - Physico-chemical Properties
| Molecular Formula | C22H20F2N4O2 |
| Molar Mass | 410.42 |
| Density | 1.286±0.06 g/cm3(Predicted) |
| Boling Point | 684.6±55.0 °C(Predicted) |
| Appearance | Light yellow crystalline solid. |
| pKa | 11.79±0.46(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
544678-85-5 - Risk and Safety
| HS Code | 29335990 |
544678-85-5 - Reference Information
| biological activity | DB04760 (compound 4) is an effective, highly selective, non-zinc chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces the neurotoxicity of paclitaxel and has anticancer activity. |
Last Update：2024-04-10 22:29:15
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CAS: 544678-85-5
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