54769-40-3
N-(methylsulfonyl)oxy succinimide
CAS: 54769-40-3
Molecular Formula: C5H7NO5S
54769-40-3 - Names and Identifiers
| Name | N-(methylsulfonyl)oxy succinimide |
| Synonyms | N-(methylsulfonyl)oxy succinimide 2,5-Dioxopyrrolidin-1-yl methanesulfonate 2,5-Pyrrolidinedione, 1-[(methylsulfonyl)oxy]- |
| CAS | 54769-40-3 |
54769-40-3 - Physico-chemical Properties
| Molecular Formula | C5H7NO5S |
| Molar Mass | 193.18 |
54769-40-3 - Introduction
N-(methylsulfonyl)oxy succinimide(N-(methylsulfonyl)oxy succinimide) is an organic compound with the chemical formula CH3SO2O-N-C4H4COO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless to slightly yellow crystalline or powdery solid.
-Solubility: It can be dissolved in water and organic solvents.
Use:
-Chemical Reactant: N-(methylsulfonyl)oxy succinimide is commonly used as a removal agent for sulfonic acid protecting groups in substrates.
-Organic synthesis: It can be used for the synthesis of amides and carboxylation reactions.
Preparation Method:
The preparation of N-(methylsulfonyl)oxy succinimide usually goes through the following steps:
1. succinic acid and sulfinic acid methyl ester (methylsulfonyl chloride) reaction in a suitable solvent to generate sulfinic acid ester (methylsulfonyl succinate).
2. the sulfinate ester reacts with carbodiimide (carbon diimide) under suitable conditions to generate N-(methylsulfonyl)oxy succinimide.
Safety Information:
- N-(methylsulfonyl)oxy succinimide should be stored away from fire and oxidizing agent, avoid exposure to sunlight.
-It decomposes at high temperatures to produce toxic fumes.
-Wear personal protective equipment such as protective gloves, goggles and protective clothing to avoid contact with skin, eyes and respiratory tract.
-In use and handling, should comply with the relevant safety procedures and handling methods.
Nature:
-Appearance: It is a colorless to slightly yellow crystalline or powdery solid.
-Solubility: It can be dissolved in water and organic solvents.
Use:
-Chemical Reactant: N-(methylsulfonyl)oxy succinimide is commonly used as a removal agent for sulfonic acid protecting groups in substrates.
-Organic synthesis: It can be used for the synthesis of amides and carboxylation reactions.
Preparation Method:
The preparation of N-(methylsulfonyl)oxy succinimide usually goes through the following steps:
1. succinic acid and sulfinic acid methyl ester (methylsulfonyl chloride) reaction in a suitable solvent to generate sulfinic acid ester (methylsulfonyl succinate).
2. the sulfinate ester reacts with carbodiimide (carbon diimide) under suitable conditions to generate N-(methylsulfonyl)oxy succinimide.
Safety Information:
- N-(methylsulfonyl)oxy succinimide should be stored away from fire and oxidizing agent, avoid exposure to sunlight.
-It decomposes at high temperatures to produce toxic fumes.
-Wear personal protective equipment such as protective gloves, goggles and protective clothing to avoid contact with skin, eyes and respiratory tract.
-In use and handling, should comply with the relevant safety procedures and handling methods.
Last Update：2024-04-10 22:29:15
