548797-51-9 - Names and Identifiers
Name | 2-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
|
Synonyms | 3-Chloro-4-cyanophenylboronic acid pinacol ester 2-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile Benzonitrile, 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
|
CAS | 548797-51-9
|
548797-51-9 - Physico-chemical Properties
Molecular Formula | C13H15BClNO2
|
Molar Mass | 263.53 |
Density | 1.16±0.1 g/cm3(Predicted) |
Melting Point | 384.9±32.0 °C(Predicted) |
Storage Condition | 2-8°C |
Sensitive | IRRITANT |
MDL | MFCD16996249 |
548797-51-9 - Upstream Downstream Industry
548797-51-9 - Introduction
Nature:
2-Chloro-4-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril is a colorless to yellowish solid. It is stable at room temperature and can be dissolved in some organic solvents, such as dimethylformamide and dichloromethane. It has a lower volatility.
Use:
2-Chloro-4-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril is an important intermediate compound commonly used in organic synthesis reactions. It can be used as a starting material for the preparation of other compounds, such as drugs, dyes and coordination compounds.
Method:
The synthesis of 2-Chloro-4-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril is usually achieved by chemical reaction. A common preparation method is to combine 4-chloro-2-nitrobenzene with 4,4, 5,5-tetramethyl -1,3, the 2-dioxaboran-2-ol is reacted and then subjected to an acylation reaction to obtain the target product.
Safety Information:
Follow chemical safety procedures when using 2-Chloro-4-(4,4, 5,5-tetramethyl-1, 3,2-dioxaborolan-2-yl)benzonitril. It may cause irritation and damage to the skin, eyes and respiratory system. Appropriate personal protective equipment, such as lab gloves, goggles and protective face shields, should be worn during operation. In case of accidental exposure to the substance, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 15:18:02