549506-47-0

549506-47-0 - Names and Identifiers

Name	2-(4-tert-butoxycarbonyl-2-oxo-piperazin-1-yl)acetic acid
Synonyms	2-Oxo-4-BOC-1-piperazineacetic acid 4-Boc-2-oxo-piperazine-1-aceticacid -N-Boc-2-oxo-piperazine-1-aceticacid 4-BOC-1-CARBOXYMETHYL-PIPERAZIN-2-ONE [4-(tert-Butoxycarbonyl)-2-oxopiperazin-1-yl]acetic acid 2-(4-tert-butoxycarbonyl-2-oxo-piperazin-1-yl)acetic acid 2-[4-(tert-Butoxycarbonyl)-2-oxo-1-piperazinyl]acetic acid 2-{4-[(tert-butoxy)carbonyl]-2-oxopiperazin-1-yl}acetic acid 4-[(1,1-Dimethylethoxy)carbonyl]-2-oxo-1-piperazineacetic acid 1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo-
CAS	549506-47-0
InChI	InChI=1/C11H18N2O5/c1-11(2,3)18-10(17)13-5-4-12(7-9(15)16)8(14)6-13/h4-7H2,1-3H3,(H,15,16)

549506-47-0 - Physico-chemical Properties

Molecular Formula	C11H18N2O5
Molar Mass	258.27
Density	1.263
Boling Point	456.2±40.0 °C(Predicted)
Flash Point	229.7°C
Vapor Presure	1.37E-09mmHg at 25°C
pKa	3.66±0.10(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.512

549506-47-0 - Risk and Safety

HS Code

29335990

549506-47-0 - Introduction

2-(a) acetic acid is an organic compound whose chemical formula is C11H16N2O5. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: about 150-152 ℃.
-Solubility: Soluble in alcohol and ester solvents, insoluble in water.
-Stability: relatively stable to light and heat.

Use:
2-(acetic acid) is commonly used as an intermediate in drug synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.

Preparation Method:
The preparation of (2-) acetic acid can usually be completed by the following steps:
1. piperazine is reacted with chloroacetic anhydride in dichloromethane to generate piperazine 4-chloroacetate.
2. React 4-chloroacetic acid piperazine with tetra-tert-butyl carbonic anhydride (t-Boc-O2CO2t) in the presence of sodium carbonate to obtain 4-chloroacetic acid).
3. Finally, the obtained acetic acid is reacted with the alcohol solution of sodium carbonate to generate the target product 2-(quartz) acetic acid.

Safety Information:
- 2-Acetic acid is a chemical and must be stored and used properly.
-Avoid inhaling its dust. Avoid contact with skin and eyes.
-Wear appropriate personal protective equipment, such as gloves, glasses and protective face masks.
-When operating in a laboratory environment, follow safe operating procedures and provide good ventilation.
-For synthetic experiments using this compound, correct chemical synthesis procedures and safe operating procedures should be followed.

Last Update：2024-04-09 21:00:56