54968-74-0
Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate
CAS: 54968-74-0
Molecular Formula: C7H9N3O3S
54968-74-0 - Names and Identifiers
54968-74-0 - Physico-chemical Properties
| Molecular Formula | C7H9N3O3S |
| Molar Mass | 215.23 |
| Density | 1.459±0.06 g/cm3(Predicted) |
| Melting Point | 203-204 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 269.9±40.0 °C(Predicted) |
| pKa | 14.06±0.50(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00848452 |
54968-74-0 - Risk and Safety
| Hazard Class | IRRITANT |
54968-74-0 - Introduction
Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate is an organic compound with the chemical structure of C8H10N4O3S. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), slightly soluble in water.
-Melting point: about 160-165°C.
Use:
- Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate is an intermediate compound commonly used in the field of drug synthesis.
-It can be used to synthesize various biologically active molecules and compounds containing thiazole structure.
Preparation Method:
Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate can be synthesized in many ways. The following is a simple preparation method:
1. prepare 1 mol of 4-carboxamido -3-thiothiazole.
2.1 mol of glycolic acid with excess ammonia reaction.
3. Mix the above two reactants at low temperature, stir and heat the reaction solution.
4. Rectification to collect the resulting product.
Safety Information:
- Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate report with no special safety precautions.
-When using, wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-During operation and storage, direct contact with skin and inhalation of dust should be avoided.
-Before use, please read the safety data form of the relevant chemical for more detailed use and safety information.
Nature:
-Appearance: White crystal or crystalline powder.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), slightly soluble in water.
-Melting point: about 160-165°C.
Use:
- Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate is an intermediate compound commonly used in the field of drug synthesis.
-It can be used to synthesize various biologically active molecules and compounds containing thiazole structure.
Preparation Method:
Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate can be synthesized in many ways. The following is a simple preparation method:
1. prepare 1 mol of 4-carboxamido -3-thiothiazole.
2.1 mol of glycolic acid with excess ammonia reaction.
3. Mix the above two reactants at low temperature, stir and heat the reaction solution.
4. Rectification to collect the resulting product.
Safety Information:
- Ethyl 4-amino-3-(aminocarbonyl)isothiazole-5-carboxylate report with no special safety precautions.
-When using, wear appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-During operation and storage, direct contact with skin and inhalation of dust should be avoided.
-Before use, please read the safety data form of the relevant chemical for more detailed use and safety information.
Last Update：2024-04-09 02:00:56
