Name | dimetridazole |
Synonyms | 1,2-Dimethyl-5-nitroimidazole 1,2-Dimethy-5-Nitro Imidazole 1,2-dimethyl-5-nitro-1H-imidazole |
CAS | 551-92-8 |
EINECS | 209-001-2 |
InChI | InChI=1/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3 |
InChIKey | IBXPYPUJPLLOIN-UHFFFAOYSA-N |
Molecular Formula | C5H7N3O2 |
Molar Mass | 141.13 |
Density | 1.36g/cm3 |
Melting Point | 177-182℃ |
Boling Point | 313.7°C at 760 mmHg |
Flash Point | 143.5°C |
Solubility | Soluble in chloroform, ethanol, dilute alkali and dilute acid; insoluble in water and ether. |
Vapor Presure | 0.000901mmHg at 25°C |
Appearance | Light yellow needle crystal or crystalline powder (yellowish-like solid) |
Merck | 14,3265 |
BRN | 130665 |
Storage Condition | 2-8℃ |
Refractive Index | 1.598 |
MDL | MFCD00047046 |
Use | Is a highly efficient, low toxicity, extended spectrum antibacterial, antigenic worm treatment or prevention drugs |
Safety Description | S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 3 |
Reference Show more | 1. [IF=10.588] Lingyu Li et al."AuNPs/NiFe-LDHs-assisted laser desorption/ionization mass spectrometry for efficient analysis of metronidazole and its metabolites in water samples."J Hazard Mater. 2022 Feb;423:126893 2. [IF=7.312] Wei Luo et al."Efficient degradation of dimetridazole during the UV/chlorine process: Kinetics, pathways, and halonitromethanes formation."Sep Purif Technol. 2022 Jun;290:120792 |
дёӯж–ҮеҗҚз§°: | дәҢз”ІзЎқе’Әе”‘ |
дёӯж–ҮеҗҢд№үиҜҚ: | дәҢз”ІзЎ«е’Әе”‘;дәҢзЎқеҹәе’Әе”‘;ең°зҫҺзЎқе”‘(дәҢз”ІзЎқе’Әе”‘);1,2-дәҢз”Іеҹә-5-зЎқеҹәе’Әе”‘,ж»ҙе’Әе”‘,иҝӘзҫҺе”‘,иҫҫзҫҺзҙ;1,2-дәҢз”Іеҹә-5-зЎқеҹәе’Әе”‘[з”ҹзү©еӯҰз”究用];1,2-дәҢз”Іеҹә-5-зЎқеҹәе’Әе”‘/ең°зҫҺзЎқе”‘;дәҢз”ІзЎқе’Әе”‘/ең°зҫҺзЎқе”‘;1,2-дәҢз”Іеҹә-5-зЎқеҹәе’Әе”‘,97%;дәҢз”ІзЎқе’Әе”‘ |
иӢұж–ҮеҗҚз§°: | 1,2-Dimethyl-5-nitroimidazole |
иӢұж–ҮеҗҢд№үиҜҚ: | DIMETRIDAZOLE;1,2-dimethyl-5-nitro-1h-imidazole;1,2-DIMETHYL-5-NITROIMIDAZOLE;1,2-dimethy-5-nitroimidazole;1,2-dimethyl-5-nitro-1h-imidazol;1,2-dimethyl-5-nitro-imidazol;1H-Imidazole, 1,2-dimethyl-5-nitro-;1H-Imidazole,1,2-dimethyl-5-nitro- |
CASеҸ·: | 551-92-8 |
еҲҶеӯҗејҸ: | C5H7N3O2 |
еҲҶеӯҗйҮҸ: | 141.13 |
EINECSеҸ·: | 209-001-2 |
зӣёе…ізұ»еҲ«: | е°ҸеҲҶеӯҗжҠ‘еҲ¶еүӮ;е’Әе”‘зұ»;й©ұиҷ«дҝқеҒҘеүӮ;йҘІж–ҷж·»еҠеүӮ;еҲҶжһҗжҮеҮҶе“Ғ;жҠ—з”ҹзҙ;е’Әе”‘;еҶңз”Ёе…Ҫз”ЁеҺҹж–ҷ;еҢ–е·Ҙ;еҶңжһ—жё”зү§дёҡз”ЁеҺҹж–ҷ;е…ҪиҚҜеҺҹж–ҷ;йЈҹе“Ғж·»еҠеүӮ;з”ҹе‘Ҫ科еӯҰжҮеҮҶе“Ғ;е·ҘдёҡеҺҹж–ҷ;еҢ–еҗҲзү©;еҢ–е·Ҙдёӯй—ҙдҪ“;е№ҝи°ұжҠ—еҺҹиҷ«иҚҜ;з”ҹеҢ–иҜ•еүӮ;е…ҪиҚҜеҺҹж–ҷиҚҜ;еҺҹж–ҷиҚҜ;е…¶д»–еҢ»иҚҜзұ»;е…»ж®–гҖҒйҘІж–ҷеҠе·ҘеҺҹж–ҷ;еҶңдёҡеҺҹж–ҷ;еҢ»иҚҜеҺҹж–ҷ;еҢ»иҚҜе…ҪиҚҜ;еҺҹж–ҷдёӯй—ҙдҪ“-еҺҹж–ҷиҚҜ;еҺҹж–ҷиҚҜ;еҢ»иҚҜеҺҹж–ҷ;дәҢз”ІзЎқе’Әе”‘;еҢ»з”ЁеҺҹж–ҷ;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;nitro-compound;EMTRYL;Broad spectrum peptides anaerobic bacteria and drug resistance;Pharmaceutical intermediates;еҺҹж–ҷ;иҚҜзү©жқӮиҙЁеҸҠдёӯй—ҙдҪ“;еҢ»иҚҜеҺҹж–ҷиҚҜ;еҢ»иҚҜгҖҒеҶңиҚҜеҸҠжҹ“ж–ҷдёӯй—ҙдҪ“;еҢ–е·Ҙжқҗж–ҷ;жңүжңәдёӯй—ҙдҪ“;е…ҪиҚҜеҢ–е·Ҙ;еҺҹиҚҜдёӯй—ҙдҪ“;еӨ§иҙ§;еҢ–еӯҰиҜ•еүӮ;е…Ҫз”ЁеҺҹж–ҷ;551-92-8;еҢ–еӯҰеҺҹж–ҷ;е·ҘдёҡеҢ–;иҝ‘жңҹдјҳеҠҝжҺЁиҚҗ;еҜ№з…§е“Ғ |
Molж–Ү件: | 551-92-8.mol |
зҶ”зӮ№ | 177-182В°C |
жІёзӮ№ | 258.15В°C (rough estimate) |
еҜҶеәҰ | 1.3818 (rough estimate) |
жҠҳе°„зҺҮ | 1.6190 (estimate) |
еӮЁеӯҳжқЎд»¶ | Inert atmosphere,2-8В°C |
жә¶и§ЈеәҰ | ethanol: soluble50mg/mL |
еҪўжҖҒ | Crystalline Powder |
й…ёеәҰзі»ж•°(pKa) | 2.81Вұ0.25(Predicted) |
йўңиүІ | white to yellow with a green cast |
ж°ҙжә¶и§ЈжҖ§ | 9.69g/L(20 ºC) |
зЁіе®ҡжҖ§ | Stable. Incompatible with strong oxidizing agents. |
NISTеҢ-еӯҰзү©и Ёд/td> | Information provided by: webbook.nist.gov (external link) |
EPAеҢ-еӯҰзү©и/td> | Information provided by: ofmpub.epa.gov (external link) |
з®Җд»Ӣ | дәҢз”ІзЎқе’Әе”‘еҸҲеҗҚиҝӘзҫҺе”‘пјҢжң¬е“Ғдёәзұ»зҷҪиүІжҲ–еҫ®й»„иүІзІүжң«пјҢж—иҮӯпјҢе‘іиӢҰпјҢйҒҮе…үйҖҗжёҗеҸҳй»‘пјҢжҳ“жә¶дәҺж°Ҝд»ҝеҸҠд№ҷйҶҮпјҢеҫ®жә¶дәҺж°ҙжҲ–д№ҷйҶҡгҖӮ |
еә”з”Ё | дәҢз”ІзЎқе’Әе”‘дё»иҰҒз”ЁдҪңе…Ҫзұ»жҠ—иҸҢиҚҜпјҢжҳҜйў„йҳІеҸҠжІ»з–—зҢӘиөӨз—ўзҡ„йҰ–йҖүиүҜиҚҜпјҢиҝҳеҸҜз”ЁдҪңйҘІж–ҷж·»еҠеүӮпјҢжңүеҲ©дәҺдҝғиҝӣз•ңзҰҪз”ҹй•ҝпјҢе°‘йҮҸз”ЁдәҺж—Ҙз”ЁеҢ–е·ҘгҖӮ |
еҢ–еӯҰжҖ§иҙЁ | жө…й»„иүІй’ҲзҠ¶з»“жҷ¶жҖ§зІүжң«пјҢж—е‘ігҖӮзҶ”зӮ№138-139в„ғгҖӮжә¶дәҺж°Ҝд»ҝгҖҒд№ҷйҶҮгҖҒзЁҖзўұеҗҲзЁҖй…ёпјҢдёҚжә¶дәҺж°ҙеҗҲд№ҷйҶҡгҖӮзӣҗй…ёзӣҗжә¶дәҺж°ҙеҗҲд№ҷйҶҮпјҢеҫ®жә¶дәҺдёҷй…®гҖӮ |
з”ЁйҖ” | жҳҜз•ңзҰҪдҝғз”ҹй•ҝеүӮе’Ңй«ҳж•ҲгҖҒдҪҺжҜ’зҡ„е№ҝи°ұжҠ—еҺҹиҷ«иҚҜгҖӮеҸҜз”ЁдәҺзҢӘйҘІж–ҷпјҢз”ЁйҮҸ50-100g/tпјӣд№ҹеҸҜз”ЁдәҺйёЎйҘІж–ҷпјҢз”ЁйҮҸ125-200g/tгҖӮ дәҢз”ІзЎқе’Әе”‘еҜ№й»‘еӨҙз»„з»Үж»ҙиҷ«гҖҒзүӣжҜӣж»ҙиҷ«гҖҒз»“иӮе°ҸиўӢиҷ«гҖҒйһӯжҜӣиҷ«зӯүеҺҹиҷ«пјҢеҸҠеқҸжӯ»еҺҢж°§дёқжқҶиҸҢгҖҒжўӯзҠ¶иҠҪиғһжқҶиҸҢгҖҒеҺҢж°”и‘Ўиҗ„зҗғиҸҢгҖҒиӮеј§иҸҢгҖҒеҜҶиһәж—ӢдҪ“иҸҢзӯүз»ҶиҸҢпјҢе…·жңүжҳҫи‘—жҠ‘еҲ¶дҪңз”ЁпјҢжҳҜжІ»з–—зҒ«йёЎй»‘еӨҙз—…еҸҠзҢӘиөӨз—ўзҡ„жңүж•ҲиҚҜзү©гҖӮиҜҘе“Ғд№ҹеҸҜдҪңдёәз”ҹй•ҝдҝғиҝӣеүӮпјҢз”Ёд»ҘдҝғиҝӣзҢӘгҖҒйёЎзҡ„з”ҹдә§еҸҠжҸҗй«ҳйҘІж–ҷиҪ¬еҢ–зҺҮгҖӮиҜҘе“ҒдҪңдёәйҘІж–ҷж·»еҠеүӮж—¶пјҢеңЁйҘІж–ҷеҠе·Ҙж—¶е…ҲжҠҠжң¬е“ҒдёҺ10-20еҖҚйҘІж–ҷйҮҸйў„ж··пјҢ然еҗҺеҶҚдёҺжүҖйңҖзҡ„йҘІж–ҷжҖ»йҮҸеқҮеҢҖж··еҗҲгҖӮжҲ–иҖ…е…ҲжҠҠжң¬е“ҒдёҺйҖӮйҮҸзҡ„иҪҪдҪ“ж··еҗҲпјҢ然еҗҺеҠиҝӣйҘІж–ҷйҮҢжҗ…жӢҢгҖӮеңЁеҠе·Ҙй…ҚеҗҲйҘІж–ҷж—¶пјҢйҖзІ’еҸҠе…¶д»–ж“ҚдҪңиҝҮзЁӢеҜ№жң¬е“Ғзҡ„ж•ҲжһңжІЎжңүеҪұе“ҚгҖӮиҜҘе“ҒеҸҜжӢҢе…ҘйҘІж–ҷпјҢд№ҹеҸҜж·»еҠдәҺйҘ®ж°ҙдёӯдҫӣз•ңзҰҪйҘ®з”ЁгҖӮз”ІзЎқе’Әе”‘жҜ’жҖ§дҪҺпјҢеҠЁзү©иҖҗеҸ—жҖ§еҘҪпјҢж—иҮҙзҷҢиҮҙз•ёдҪңз”ЁгҖӮиҜҘе“ҒеңЁиӮйҒ“дёӯиў«иҝ…йҖҹеҗёж”¶пјҢеҲҶеёғдәҺеҗ„з»„з»ҮдёӯпјҢз»ҸиғҶйҒ“иҝӣиӮгҖҒиӮқеҫӘзҺҜгҖӮеңЁзҰҪз•ңдҪ“еҶ…пјҢз»Ҹж°§еҢ–гҖҒиҝҳеҺҹд»Ји°ўеҗҺжҺ’еҮәдҪ“еӨ–гҖӮиғҙдҪ“дёӯзҡ„ж®Ӣз•ҷзү©пјҢеңЁ48hеҗҺжҲ–зғ№и°ғеҗҺпјҢз»қеӨ§йғЁеҲҶиў«зҙеқҸгҖӮеңЁеңҹеЈӨдёӯеҲҶи§Јд№ҹиҫғеҝ«пјҢж•…дёҚдјҡеҜјиҮҙеҜ№зҺҜеўғзҡ„жұЎжҹ“гҖӮиҜҘе“ҒзЁіе®ҡпјҢдәҺе№ІзҮҘеӨ„еңЁ37в„ғд»ҘдёӢеҸҜдҝқеӯҳдәҢе№ҙгҖӮ жҳҜй«ҳж•ҲгҖҒдҪҺжҜ’гҖҒи¶…е№ҝи°ұжҠ—иҸҢгҖҒжҠ—еҺҹиҷ«зҡ„жІ»з–—жҲ–йў„йҳІиҚҜзү© е№ҝи°ұжҠ—еҺҢж°§иҸҢе’ҢжҠ—еҺҹиҷ«иҚҜпјҢеҜ№з»„з»Үж»ҙиҷ«гҖҒеқҮжңүжқҖзҒӯдҪңз”ЁпјҢеҜ№зҗғиҷ«д№ҹжңүдёҖе®ҡзҡ„жҠ‘еҲ¶дҪңз”ЁгҖӮ |
з”ҹдә§ж–№жі• | д»Ҙд№ҷдәҢйҶӣдёәиө·е§ӢеҺҹж–ҷпјҢдёҺд№ҷйҶӣгҖҒж°ЁзҺҜеҗҲпјҢеҫ—2-з”Іеҹәе’Әе”‘пјҲC4H5N2пјҢ[693--98-1]пјүгҖӮ然еҗҺзЎқеҢ–пјҢеҫ—2-з”Іеҹә-5-зЎқеҹәе’Әе”‘пјҲC4H6N3O2пјҢ[696-23-1]гҖӮжңҖеҗҺд»ҘзЎ«й…ёдәҢз”Ій…Ҝз”ІеҹәеҢ–еҚіеҫ—з”ІзЎқе’Әе”‘гҖӮдёӯй—ҙдҪ“2-з”Іеҹәе’Әе”‘д№ҹеҸҜз”ұд№ҷдәҢиғәдёҺд№ҷи…ҲзҺҜеҗҲеҫ—еҲ°2-з”Іеҹәе’Әе”‘е•үпјҢ然еҗҺеҠжҙ»жҖ§й•ҚеӮ¬еҢ–и„ұж°ўиҖҢеҫ—гҖӮ д»Ҙ2-з”Іеҹәе’Әе”‘дёәеҺҹж–ҷпјҢз»ҸзЎқеҢ–гҖҒз”Ій…ҜеҢ–иҖҢеҫ—гҖӮе°Ҷ40gе°ҝзҙжә¶дәҺ100mLж°ҙдёӯпјҢеҠе…Ҙ40mLжө“зЎқй…ёпјҢеҫ—жә¶ж¶Ів…гҖӮжҺ§еҲ¶жё©еәҰе°ҸдәҺ50в„ғпјҢе°Ҷ70g2-з”Іеҹәе’Әе”‘зј“ж…ўеҠе…Ҙ200mLе·ҘдёҡзЎ«й…ёдёӯпјҢеҫ—еҲ°жә¶ж¶Ів…ЎгҖӮе°Ҷжә¶ж¶Ів…Ўж…ўж…ўеҖ’е…Ҙжә¶ж¶Ів…дёӯпјҢеңЁе®Өжё©дёӢж”ҫзҪ®24hпјҢ然еҗҺжҗ…жӢҢеҚҮжё©иҮі80в„ғеҸҚеә”2hпјҢеҚҮжё©иҮі110в„ғеҸҚеә”0.5hгҖӮеҶ·еҚҙиҮі80в„ғж»ҙеҠжө“зЎқй…ё200mLпјҢеҚҮжё©иҮі120в„ғжҗ…жӢҢеҸҚеә”2hпјҢжңҖеҗҺдәҺ150в„ғд»ҘдёӢи’ёеҮәеӨҡдҪҷзҡ„зЎқй…ёгҖӮеҶ·еҚҙиҮі40в„ғпјҢз”Ё400mLж°ҙзЁҖйҮҠпјҢж°Ёж°ҙи°ғPH=3.5-4.0гҖӮеҶ·иҮіе®Өжё©пјҢз»ҸиҝҮж»ӨгҖҒж°ҙжҙ—гҖҒе№ІзҮҘгҖҒеҫ—2-з”Іеҹә-5-зЎқеҹәе’Әе”‘83.8gпјҲзҶ”зӮ№248-250в„ғпјүпјҢдә§зҺҮ77.3%гҖӮеңЁдёүеҸЈзғ§з“¶дёӯеҠе…ҘдёҠиҝ°дә§е“Ғ50gе’Ң85%зҡ„з”Ій…ё60mLпјҢеҠзғӯиҮі80в„ғпјҢдәҺ30minеҶ…ж»ҙеҠзЎ«й…ёдәҢз”Ій…Ҝ[пјҲCH3пјү2SO4]60gпјҢйҡҸеҗҺеҸҚеә”0.5hгҖӮ然еҗҺи’ёеҺ»жә¶еүӮпјҢеҠе…Ҙж°ҙ50mLпјҢи’ёйҰҸдҪҷй…ёпјҢеҶҚеҠе…Ҙж°ҙ50mLпјҢж°Ёж°ҙи°ғиҠӮPH=2.5гҖӮеҶ·еҚҙиҮіе®Өжё©пјҢз»ҸиҝҮж»ӨпјҢж»ӨжёЈзғҳе№Іеҫ—жңӘеҸҚеә”2-з”Іеҹә-5-зЎқеҹәе’Әе”‘12.4gгҖӮж»Өж¶Із”Ёжҙ»жҖ§зӮӯи„ұиүІеҗҺпјҢеҠе…Ҙж°Ёж°ҙи°ғPH=6-7пјҢиҝҮж»ӨгҖҒжҙ—ж¶ӨгҖҒе№ІзҮҘеҫ—дә§е“Ғ29.3g(зҶ”зӮ№138-140в„ғ)пјҢдә§зҺҮ70.3%гҖӮжҖ»дә§зҺҮ54.3%. |
еҚұйҷ©е“ҒжҮеҝ— | Xi |
еҚұйҷ©зұ»еҲ«зҒ | 36/37/38 |
е®үе…ЁиҜҙжҳҺ | 26-36-36/37-22 |
RTECSеҸ· | NI5075000 |
жө·е…ізј–зҒ | 29332900 |
дёҠжёёеҺҹж–ҷ | зЎқй…ё-->зЎ«й…ёдәҢз”Ій…Ҝ-->д№ҷдәҢйҶӣ-->е·ҘдёҡзЎ«й…ё-->дёүеҸЈзғ§з“¶-->2-з”Іеҹәе’Әе”‘-->2-з”Іеҹә-5-зЎқеҹәе’Әе”‘-->2-з”Іеҹәе’Әе”‘е•ү-->з”ІзЎқе’Әе”‘ |