552331-44-9

552331-44-9 - Names and Identifiers

Name	4,7-Dichloropyrido[2,3-d]pyrimidine
Synonyms	4,7-Dichloro-pyrido[2,3-d... 4,7-Dichloropyrido[2,3-d]pyrimidine 4,7-Dichloro-pyrido[2,3-d]pyrimidine Pyrido[2,3-d]pyrimidine, 4,7-dichloro- Pyrido[2,3-d]pyrimidine, 4,7-dichloro- (9CI)
CAS	552331-44-9
InChI	InChI=1/C7H3Cl2N3/c8-5-2-1-4-6(9)10-3-11-7(4)12-5/h1-3H

552331-44-9 - Physico-chemical Properties

Molecular Formula	C7H3Cl2N3
Molar Mass	200.02
Density	1.573±0.06 g/cm3(Predicted)
Boling Point	327.2±37.0 °C(Predicted)
Flash Point	181.634°C
Vapor Presure	0mmHg at 25°C
pKa	-1.32±0.30(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.682

552331-44-9 - Introduction

4,7-Dichloropyrido[2,3-d]pyrimidine is an organic compound with the chemical formula C8H4Cl2N2. The following is a description of its nature, use, preparation and safety information:

Nature:
4,7-Dichloropyrido[2,3-d]pyrimidine is a colorless to pale yellow crystalline solid. Its melting point is about 148-150 degrees Celsius. At room temperature, it is almost insoluble in water, but can be dissolved in most common organic solvents. It is a hygroscopic substance and is relatively unstable in air.

Use:
4,7-Dichloropyrido[2,3-d]pyrimidine has a variety of applications in the field of pharmaceutical and pesticide chemistry. As a pharmaceutical intermediate, it plays an important role in the synthesis of anticancer drugs and other bioactive compounds. In the field of pesticides, it can be used to make products such as pesticides and herbicides.

Preparation Method:
The preparation of 4,7-Dichloropyrido[2,3-d]pyrimidine is usually achieved by chemical synthesis. A common method is to react 2-chloropyridine with o-dichlorophenol under basic conditions, followed by further cyclization to form the target product. The specific synthesis path may vary, and this is just one of the common methods.

Safety Information:
Regarding the safety information of 4,7-Dichloropyrido[2,3-d]pyrimidine, the following aspects need to be noted:

1. It is an organic compound that may have certain toxicity to the human body. When handling and using, should comply with the relevant safety procedures, and take appropriate protective measures, such as wearing gloves, wearing protective clothing, to ensure good ventilation.

2. Avoid inhaling the dust or vapor of the solution, as it may cause irritation to the respiratory tract and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

3. in the process of storage and transportation, it is necessary to avoid contact with strong oxidants, strong acids and other substances to avoid dangerous reactions.

4. The use and disposal of this compound should strictly comply with local regulations and regulations. If necessary, refer to the relevant safety data sheet or consult a professional.

Last Update：2024-04-09 19:05:50