55273-57-9
5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride
CAS: 55273-57-9
Molecular Formula: C7H7Cl2NO
55273-57-9 - Names and Identifiers
| Name | 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride |
| Synonyms | 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride 5-(ChloroMethyl)pyridine-2-carbaldehyde hydrochloride |
| CAS | 55273-57-9 |
55273-57-9 - Physico-chemical Properties
| Molecular Formula | C7H7Cl2NO |
| Molar Mass | 192.04258 |
55273-57-9 - Introduction
5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride is an organic compound with the chemical formula C7H6Cl2N2O · HCl. Its nature is as follows:
Appearance: White crystalline solid
Solubility: Soluble in water and some organic solvents, such as alcohols and ethers
Melting point: about 165-169 degrees Celsius
5-(Chloromethyl) The main applications of pyridine-2-carbaldehyde hydrochloride are as follows:
1. Organic synthesis: It is an important organic synthesis intermediate, which can be used to synthesize various organic compounds.
2. Pharmaceutical field: It has a wide range of applications in the synthesis of drugs, such as anti-tumor drugs and antiviral drugs.
3. Chemical analysis: It can be used to analyze reactions and reagents in chemistry.
Preparation Method: 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride is usually prepared by the following steps:
First, 5-chloropyridin-2-ol is reacted with chlorocarbonic anhydride to produce 5-chloropyridine-2-carboxylate.
Then, 5-chloropyridine-2-carboxylate is reacted with aldehyde to produce 5-chloropyridine-2-aldehyde.
Finally, 5-chloropyridine-2-aldehyde is reacted with hydrochloric acid to form 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride.
Safety information: 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride is relatively stable under general operating conditions, but it is still necessary to pay attention to safe use. When in use, wear appropriate protective gloves, glasses and protective clothing to ensure good ventilation. If inhaled, contact with skin or ingested, rinse immediately with water and seek medical attention.
Appearance: White crystalline solid
Solubility: Soluble in water and some organic solvents, such as alcohols and ethers
Melting point: about 165-169 degrees Celsius
5-(Chloromethyl) The main applications of pyridine-2-carbaldehyde hydrochloride are as follows:
1. Organic synthesis: It is an important organic synthesis intermediate, which can be used to synthesize various organic compounds.
2. Pharmaceutical field: It has a wide range of applications in the synthesis of drugs, such as anti-tumor drugs and antiviral drugs.
3. Chemical analysis: It can be used to analyze reactions and reagents in chemistry.
Preparation Method: 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride is usually prepared by the following steps:
First, 5-chloropyridin-2-ol is reacted with chlorocarbonic anhydride to produce 5-chloropyridine-2-carboxylate.
Then, 5-chloropyridine-2-carboxylate is reacted with aldehyde to produce 5-chloropyridine-2-aldehyde.
Finally, 5-chloropyridine-2-aldehyde is reacted with hydrochloric acid to form 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride.
Safety information: 5-(Chloromethyl)pyridine-2-carbaldehyde hydrochloride is relatively stable under general operating conditions, but it is still necessary to pay attention to safe use. When in use, wear appropriate protective gloves, glasses and protective clothing to ensure good ventilation. If inhaled, contact with skin or ingested, rinse immediately with water and seek medical attention.
Last Update：2024-04-09 21:01:54
