Name | 2-Coumaranone |
Synonyms | 2-Coumaranone 2-COUMARANONE 2-Coumaronone Benzo-furanone 2H-BENZOFURANONE 2(3H)-BENZOFURANONE 2(3H)-Benzofuranone 3H-Benzofuran-2-one BENZOFURAN-2[3H]-ONE Benzofuran-2(3H)-one 1-benzofuran-2(3H)-one Coumarone-2(3H)-ketone 1-Benzofuran-2(3H)-one Benzo[b]furan-2(3H)-one 2,3-dihydrobenzofuran-2-one 2,3-Dihydrobenzofuran-2-one 2,3-Dihydrobenzo[b]furan-2-one |
CAS | 553-86-6 |
EINECS | 209-052-0 |
InChI | InChI=1/C8H6O2/c9-8-5-6-3-1-2-4-7(6)10-8/h1-4H,5H2 |
InChIKey | ACZGCWSMSTYWDQ-UHFFFAOYSA-N |
Molecular Formula | C8H6O2 |
Molar Mass | 134.13 |
Density | 1,22 g/cm3 |
Melting Point | 49-51°C(lit.) |
Boling Point | 248-250°C(lit.) |
Flash Point | >230°F |
Solubility | H2O: soluble3.8g/L at 30°C |
Vapor Presure | 0.027-0.24Pa at 10-30℃ |
Appearance | Crystalline powder |
Color | White to yellow-orange |
BRN | 114689 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.4800 (estimate) |
MDL | MFCD00005856 |
Use | 2(3H)-Benzofuranone |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R36/38 - Irritating to eyes and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 3 |
HS Code | 29322090 |
LogP | 1.347 |
surface tension | 63.8mN/m at 1g/L and 20 ℃ |
Overview | benzofuranones are important intermediates in organic synthesis, which can be used in the synthesis of pharmaceuticals, pesticides and new antioxidants. |
preparation | with O-nitrotoluene as raw material, O-nitrophenylacetic acid was prepared first, and then reduced by diazotization reaction and hydrolysis to obtain benzofuranone, it is not necessary to separate the O-hydroxyphenylacetic acid in the middle. Although the raw materials of this method are cheap and easy to obtain, the operation is simple, but the route is longer. |
Application | mainly used for the synthesis of pesticide azoxystrobin |