55750-49-7

55750-49-7 - Names and Identifiers

Name	ethyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
Synonyms	NSC 266054 N-Carbethoxymaleimide N-Ethoxycarbonylmaleimide N-Ethyoxycarbonyl MaleiMide Ethyl 2,5-Dioxopyrrole-1-carboxylate ethyl 2,5-dioxo-2H-pyrrole-1(5H)-carboxylate ethyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate Ethyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2,5-dioxo-, ethyl ester
CAS	55750-49-7
InChI	InChI=1/C7H7NO4/c1-2-12-7(11)8-5(9)3-4-6(8)10/h3-4H,2H2,1H3

55750-49-7 - Physico-chemical Properties

Molecular Formula	C7H7NO4
Molar Mass	169.13
Density	1.407±0.06 g/cm3(Predicted)
Boling Point	257.3±23.0 °C(Predicted)
Flash Point	109.4°C
Vapor Presure	0.0147mmHg at 25°C
pKa	-3.11±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.535

55750-49-7 - Introduction

Ethyl 2,5-dioxo-2, chemical formula C7H7NO4, its properties, uses, preparation and safety information are as follows:

Nature:
-Appearance: ethyl 2,5-dioxo-2, is a colorless to pale yellow solid.
-Solubility: It is soluble in ether, chloroform and alcohol solvents.
-Melting point: Its melting point range is between 105-115°C.

Use:
- ethyl 2,5-dioxo-2, can be used as an intermediate in organic synthesis.
-It is used in the field of medicine for the synthesis of antibiotics, anticancer drugs and physiologically active compounds.

Preparation Method:
Ethyl 2,5-dioxo-2, the preparation method can be realized by the following steps:
1. first, pyrrole-1-ketone and acetic anhydride are reacted with sulfuric acid or acetic acid to generate the addition product ethyl 2,5-dioxo-2, pyridine.
2. Further treatment of the addition product, through dehydrogenation and hydrolysis reaction, to obtain a higher purity of ethyl 2,5-dioxo-2, the product.

Safety Information:
ethyl 2,5-dioxo-2, is generally stable and harmless under normal operating conditions. However, due to individual differences and the potential risks associated with its chemical properties, caution is still required in the use and handling of this substance.
-Skin contact: Avoid skin contact and wear gloves if necessary.
-Inhalation: It should be operated in a well-ventilated place to avoid inhaling its dust or vapor.
-Eye contact: In case of eye contact, rinse immediately with plenty of water and seek medical attention.

In view of the differences in chemical properties and safety requirements, please read the relevant safety instructions or consult a professional when using or handling ethyl 2,5-dioxo-2.

Last Update：2024-04-09 21:04:16