Name | ROSAPROSTOL |
Synonyms | C-83 Rosal IBI-C83 AY-22469 ROSAPROSTOL Rosaprostolum Einecs 260-341-8 Rosaprostolum [latin] |
CAS | 56695-65-9 |
EINECS | 260-341-8 |
Molecular Formula | C18H34O3 |
Molar Mass | 298.46 |
Density | 0.981±0.06 g/cm3(Predicted) |
Boling Point | 442.1±18.0 °C(Predicted) |
pKa | 4.78±0.10(Predicted) |
Physical and Chemical Properties | Chemical properties of oil. Rosaprostol Sodium: C18H33NaO3. White solid. Acute toxicity LD50 mice and rats (mg/kg): about 3000 oral;>5000 oral. |
Use | Uses for gastric ulcer, duodenal ulcer, gastritis, duodenitis, iatrogenic gastroduodenal lesions. |
The mercurization of cis-12-hydroxyoctadecarbon-9-enoic acid gives 9, 12-dihydroxyoctadecarbonate. Re-oxidation to obtain diketone, which is cyclized under the action of sodium hydroxide to obtain 7-(2-hexyl-5-oxopentenyl) heptanoic acid. Finally, it is reduced to obtain roxatoprostol.