56741-95-8

Name	Bropirimine
Synonyms	U-54461 PNU-54461 Bropirimine 2-Amino-5-bromo-6-phenylpyrimidin-4-ol 2-Amino-5-bromo-6-phenylpyrimidin-4(1H)-one 2-Amino-5-bromo-6-phenylpyrimidin-4(3H)-one 2-AMINO-4-HYDROXY-5-BROMO-6-PHENYLPYRIMIDINE 2-AMINO-5-BROMO-4-HYDROXY-6-PHENYLPYRIMIDINE 5-Bromo-6-phenyl-2,3-dihydro-2-iminopyrimidin-4(1H)-one
CAS	56741-95-8

Hazard Symbols	Xn - Harmful
Risk Codes	R63 - Possible risk of harm to the unborn child R62 - Possible risk of impaired fertility
WGK Germany	3
RTECS	UW7351300

use	brompiridine is an aryl pyrimidine anti-metabolic anti-tumor drug, a bladder cancer chemotherapy drug jointly developed by the United States and Japan.
biological activity	Bropirimine is a synthetic agonist of toll-like receptor 7 (TLR7). Bropirimine the production of IFN-β mediated by TLR7 inhibits the differentiation of osteoclast precursor cells into osteoclasts. Bropirimine is an orally active immunomodulator with anticancer activity in orthotopic transitional cell carcinoma (CIS) of the bladder and upper urinary tract.
category	toxic substances
toxicity classification	poisoning
acute toxicity	oral-rat LD50:>3200 mg/kg
flammability hazard characteristics	combustible; combustion produces toxic nitrogen oxides and bromide smoke
storage and transportation characteristics	warehouse ventilation and low temperature drying
fire extinguishing agent	dry powder, foam, sand, carbon dioxide, mist water

Last Update：2024-04-09 02:00:07

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Mobile: 18021002903
QQ: 3008007409

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56741-95-8

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