5678-45-5

5678-45-5 - Names and Identifiers

Name	3-Amino-3-(4-methoxyphenyl)propionic acid
Synonyms	RARECHEM AK HC T257 DL--(p-Methoxyphenyl)alanine DL-BETA-(P-METHOXYPHENYL)ALANINE 3-Amino-3-(4-Methoxyphenyl)Propanoic Acid 3-Amino-3-(4-methoxyphenyl)propionic acid 3-AMINO-3-(4-METHOXYPHENYL)PROPANOIC ACID 3-AMINO-3-(P-METHOXYPHENYL)PROPIONIC ACID 3-AMINO-3-(4-METHOXY-PHENYL)-PROPIONIC ACID DL-3-AMINO-3-(4-METHOXY-PHENYL)-PROPIONIC ACID
CAS	5678-45-5

5678-45-5 - Physico-chemical Properties

Molecular Formula	C10H13NO3
Molar Mass	195.22
Density	1.1926 (rough estimate)
Melting Point	230°C (dec.)(lit.)
Boling Point	331.88°C (rough estimate)
Appearance	powder to crystal
Color	White to Almost white
pKa	3.74±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.5150 (estimate)

5678-45-5 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Class	IRRITANT

5678-45-5 - Introduction

3-Amino-3-(4-methoxyphenyl)propionic acid is an organic compound with the chemical formula C11H15NO3.

Nature:
-Appearance: Colorless solid
-Melting point: about 130-135°C
-Solubility: It is less soluble in water and easier to dissolve in organic solvents, such as ethanol and acetone.

Use:
3-Amino-3-(4-methoxyphenyl)propionic acid is a pharmaceutical intermediate commonly used in the synthesis of drugs, especially for the synthesis of plant growth regulators and glyphosate herbicides.

Preparation Method:
3-Amino-3-(4-methoxyphenyl)propionic acid can be synthesized by the following steps:
1. Reaction of 4-methoxybenzaldehyde with bromoacetone to obtain 3-(4-methoxyphenyl) acetone.
2.3-(4-methoxyphenyl) acetone is reacted with ammonia water to generate 3-amino -3-(4-methoxyphenyl) acetone.
3. finally, 3-amino -3-(4-methoxyphenyl) acetone is dehydrated to obtain 3-Amino-3-(4-methoxyphenyl)propionic acid.

Safety Information:
- 3-Amino-3-(4-methoxyphenyl)propionic acid belongs to general organic compounds and has certain toxicity.
-During operation, you should wear appropriate personal protective equipment, such as gloves and glasses, to avoid contact with skin or eyes.
-When heating or dissolving 3-Amino-3-(4-methoxyphenyl)propionic acid, care should be taken to prevent the release of toxic gases.
-It should be stored in a dry, cool place, away from fire and high temperature.

Last Update：2024-04-09 19:05:50