Name | Calcium Butyrate |
Synonyms | CALCIUM BUTYRATE Calcium Butyrate calciumdibutyrate Calcium dibutyrate Calcium dibutanoate calcium dibutanoate Butanoicacid,calciumsalt BUTYRIC ACID CALCIUM SALT Dibutyric acid calcium salt Bisbutanoic acid calcium salt |
CAS | 5743-36-2 |
EINECS | 227-265-7 |
InChI | InChI=1/2C4H8O2.Ca/c2*1-2-3-4(5)6;/h2*2-3H2,1H3,(H,5,6);/q;;+2/p-2 |
Molecular Formula | C8H14CaO4 |
Molar Mass | 214.27 |
Density | 1.30 g/cm3 |
Melting Point | >300°C |
Boling Point | 164.3°C at 760 mmHg |
Flash Point | 69.7°C |
Solubility | DMSO (Soluble), Methanol (Slightly) |
Vapor Presure | 1.35mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | Room Temperature, under inert atmosphere |
Use | For the pharmaceutical industry |
preparation | butyric acid 88.11g(1.0mol,1.0eq) with stirring at room temperature dissolve 5 batches in 108.5 aqueous solution containing 45.0g of sodium hydroxide, and slowly add 0.5 ml of aqueous solution containing 0.5g (mol, eq) of calcium chloride Dropwise to the reaction solution, after feeding, the reaction solution was stirred for 1h. The reaction solution was heated to 70 ℃ for 0.5h, and was filtered while hot. The filter cake was washed with hot water until the filtrate was neutral, after drying under reduced pressure at 50 °c, 155.77g of calcium butyrate was obtained, and the yield was 72.7%. |
products and applications | 1. Application of calcium butyrate in the preparation of anti-Diarrhea feed additives for animals Application of calcium butyrate in anti-Diarrhea related animals are farm animals including livestock and poultry at various growth stages, the domestic animals include pigs, cattle, sheep, horses, rabbits, dogs, cats or donkeys at various growth stages, and the poultry includes chickens, turkeys, Guinea chickens, duck, Goose, pigeon or quail, etc. In the anti-Diarrhea application of the above animals, if the calcium butyrate is added to the feed, the dosage used in the feed is 300-10000ppm in terms of calcium butyrate and feed weight, the optimum dosage range is 400-10000ppm for livestock at each growth stage, and the corresponding reduction to 300-10000ppm for poultry at each growth stage. The study found that calcium butyrate has a role in the prevention and control of various types of Diarrhea, thus providing a Diarrhea control of anti Diarrhea feed additives for animal breeding, the use of simple and low dosage, it provides an economical, easy, safe and environmentally friendly Diarrhea control method for animal husbandry, which will greatly reduce the economic losses caused by Diarrhea in animal breeding, improve the overall health of the animal. 2. studies have shown that calcium butyrate is a new type of anabolic nutritional agent, which can reduce human body fat and reduce muscle protein consumption, helps muscle recovery and reduce muscle damage caused by overwork, can improve exercise intensity and endurance. A study of the latest and most important nutritional supplements from the American Association of Sports Medicine in the United States of America, Marley, Lanzhou, valdemo, shows that calcium butyrate is a powerful anti-muscle-splitting agent. Researchers at the University of Portugal's sports science department studied the effects of calcium butyrate on muscle braking, which increases intracellular catabolism, leading to muscle atrophy and muscle fiber damage, using adult male rats for experiments, half as a control group, the other half of the daily administration of calcium butyrate, for a week, the right lower limb of the experimental animals with plastic splints to give the brake including the knee and manic joint fixed in a relaxed position. The results showed that when the muscle tissue was analyzed after removing the fixation, the muscle fiber damage of the rats in the calcium butyrate group was significantly less than that in the control group, and the volume of the immobilized muscle and the area of the muscle fiber were also significantly more than that in the control group. Another study is that calcium butyrate can increase muscle strength and can significantly reduce the amount of "bad cholesterol" in people with high cholesterol. In the current feed additive market, calcium butyrate is mainly based on its ability to increase animal muscle strength, To improve the characteristics of animal immunity, used to enhance the immunity of livestock and poultry, improve the disease resistance, improve the production performance of livestock and poultry. |
Use | for pharmaceutical industry |