Name | 8-Aminoquinoline |
Synonyms | nc066 wr6920 AKOS AUF01700 8-Quinolinamine ASISCHEM Z74664 quinolin-8-amine 8-amino-quinolin QUINOLIN-8-AMINE 8-Aminoquinoline Quinoline, 8-amino- TIMTEC-BB SBB004126 |
CAS | 578-66-5 |
EINECS | 209-427-9 |
InChI | InChI=1/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2 |
Molecular Formula | C9H8N2 |
Molar Mass | 144.17 |
Density | 1.1148 (estimate) |
Melting Point | 60-65 °C (lit.) |
Boling Point | 174 °C/26 mmHg (lit.) |
Flash Point | 174°C/26mm |
Water Solubility | slightly soluble |
Solubility | Insoluble in water, soluble in ethanol, acetone, gasoline, benzene. |
Vapor Presure | 0.00215mmHg at 25°C |
Appearance | Crystalline Powder |
Color | Green to beige-brown |
BRN | 114474 |
pKa | pK1: 3.99(+1) (20°C,μ=0.01) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Sensitive | Air Sensitive |
Refractive Index | 1.7080 (estimate) |
MDL | MFCD00006809 |
Use | Used as a pharmaceutical Intermediate |
Risk Codes | R68 - Possible risk of irreversible effects R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/38 - Irritating to eyes and skin. |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. |
UN IDs | UN2811 |
WGK Germany | 3 |
RTECS | VA9627000 |
TSCA | Yes |
HS Code | 29334990 |
Hazard Note | Harmful/Irritant/Air Sensitive |
Hazard Class | IRRITANT |
Toxicity | mmo-sat 50 mg/plate MUREAV 39,285,77 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Use | 8-aminoquinoline is an organic compound in which the 8-position of the quinoline ring is substituted with an amino group, it can be used as a pharmaceutical intermediate. pharmaceutical and pesticide intermediates used as pharmaceutical intermediates |
preparation | 8-aminoquinoline can be obtained by reduction of 8-nitroquinoline with hydrogen in the presence of a cobalt-molybdenum sulfide catalyst. |
category | toxic substances |
flammability hazard characteristics | flammability; Toxic NOx smoke from combustion |
storage and transportation characteristics | warehouse ventilation and low temperature drying |
extinguishing agent | dry powder, foam, sand, carbon dioxide, water mist |