58-25-3
Chlordiazepoxide
CAS: 58-25-3
Molecular Formula: C16H14ClN3O
58-25-3 - Names and Identifiers
58-25-3 - Physico-chemical Properties
| Molecular Formula | C16H14ClN3O |
| Molar Mass | 299.75 |
| Density | 1.2967 (rough estimate) |
| Melting Point | 230-232°C |
| Boling Point | 549.0±60.0 °C(Predicted) |
| Flash Point | 9℃ |
| Water Solubility | 2g/L(room temperature) |
| Solubility | Practically insoluble in water, sparingly soluble in ethanol (96 per cent) |
| Vapor Presure | 4.18E-12mmHg at 25°C |
| pKa | 4.8(at 25℃) |
| Storage Condition | Controlled Substance, -20°C Freezer, Under Inert Atmosphere |
| Refractive Index | 1.6490 (estimate) |
| Physical and Chemical Properties | Pale yellow crystalline powder. Melting point 236- 236.5 ° C, soluble in ether, chloroform or dichloromethane, water-soluble. There is a slight odor, bitter taste. Its hydrochloride,[438-41-5], is a white crystalline powder, melting point 213 ℃, soluble in water. |
| Use | For the treatment of Anxiety, fear, Sleep Initiation and Maintenance Disorders, muscle spasms, epilepsy and convulsions and other conditions |
58-25-3 - Risk and Safety
| Risk Codes | R11 - Highly Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R39/23/24/25 - |
| Safety Description | S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3249 |
| WGK Germany | 1 |
| HS Code | 2933910000 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 oral in rabbit: 590mg/kg |
58-25-3 - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| chlordiazepine is a weak neuroleptic with sedative, anti-Anxiety, anticonvulsant and muscle relaxant effects. Mainly for the treatment of anxiety disorders, obsessive-compulsive neurosis, neurasthenia Sleep Initiation and Maintenance Disorders and high blood pressure. Combined with other antiepileptic drugs can inhibit Grand Mal or petit mal seizures. Long-term use of a large number of addiction. Use? For the treatment of Anxiety, fear, Sleep Initiation and Maintenance Disorders, muscle spasms, epilepsy and convulsions and other conditions. | |
| purpose | This product is a weak tranquilizer with sedative, anti-Anxiety, anticonvulsant and muscle relaxation effects. Mainly for the treatment of anxiety disorders, obsessive-compulsive neurosis, neurasthenia Sleep Initiation and Maintenance Disorders and high blood pressure. Combined with other antiepileptic drugs can inhibit Grand Mal or petit mal seizures. Long-term use of a large number of addiction. for the treatment of Anxiety, fear, Sleep Initiation and Maintenance Disorders, muscle spasms, seizures and other disorders |
| production method | 2-amino-5-chloro-benzophenone was refluxed with hydroxylamine hydrochloride in ethanol for 10 hours, 2-amino-5-chloro-benzophenone oxime is obtained by cyclization and ring extension. The crude product is recrystallized with ethanol and decolorized with activated carbon to obtain the finished product. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-10 22:29:15
