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5927-18-4

Trimethyl phosphonoacetate

CAS: 5927-18-4

Molecular Formula: C5H11O5P

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5927-18-4 - Names and Identifiers

Name Trimethyl phosphonoacetate
Synonyms TMPA
TriMethyl phosphonoacetat
Trimethyl phosphonoacetate
Trimethyl phosphoroacetate
methyl (dimethoxyphosphoryl)acetate
Dibenzyloxyphosphoiyl three Methyl acetate
(Carboxymethyl)phosphonic acid trimethyl ester
Aceticacid, 2-(diMethoxyphosphinyl)-, Methyl ester
Dimethyl methoxycarbonylmethylphosphonate~Phosphonoacetic acid trimethyl ester
Dimethylphosphonoacetic Acid Methyl EsterMethyl DimethylphosphonoacetatePhosphonoacetic Acid Trimethyl Ester
CAS 5927-18-4
EINECS 227-663-0
InChI InChI=1/C5H11O5P/c1-8-5(6)4-11(7,9-2)10-3/h4H2,1-3H3

5927-18-4 - Physico-chemical Properties

Molecular FormulaC5H11O5P
Molar Mass182.11
Density1.125g/mLat 25°C(lit.)
Melting Point242 °C
Boling Point118°C0.85mm Hg(lit.)
Flash Point>230°F
Water SolubilitySlightly miscible with water.
Solubility DMSO
Vapor Presure0.000577mmHg at 25°C
AppearanceLiquid
Specific Gravityapproximate 1.265ｇ/ml (20℃)
ColorClear colorless to light yellow
BRN1865177
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
Refractive Indexn20/D 1.437(lit.)

5927-18-4 - Risk and Safety

Safety DescriptionS23 - Do not breathe vapour.
S24/25 - Avoid contact with skin and eyes.
WGK Germany3
FLUKA BRAND F CODES9
TSCAYes
HS Code29310095

5927-18-4 - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.628 ml13.141 ml26.283 ml
5 mM0.526 ml2.628 ml5.257 ml
10 mM0.263 ml1.314 ml2.628 ml
5 mM0.053 ml0.263 ml0.526 ml
Last Update：2024-01-02 23:10:35

5927-18-4 - Reference Information

NIST chemical information information provided by: webbook.nist.gov (external link)
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Introduction trimethylphosphonyl acetate is a clear colorless to light yellow liquid that can be used as a pharmaceutical intermediate.
Application trimethyl acetate phosphate can be used in intramolecular Mannich-type reaction to form sarainA-type diazepine tricyclic nucleus; for organometallic-catalyzed oxmichael reaction; For isopentene reaction and geranyl reaction of oxindole; For intramolecular Horner-Wadsworth- Emmons reaction; For olefin cross-metathesis/heterocyclic reaction.
purpose IHT-FCTMPA is an important class of Wittig-horner reagents, which is also used in the manufacture of vitamin compounds, drugs, important intermediates of natural compounds such as insect pheromones.
Last Update：2024-04-10 22:29:15
5927-18-4
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Nantong Reform Petro-Chemical CO., LTD.
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Product Name: Trimethyl phosphonoacetate Request for quotation
CAS: 5927-18-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Trimethyl phosphonoacetate Request for quotation
CAS: 5927-18-4
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Email: sales@tnjchem.com
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Product Name: Trimethyl phosphonoacetate Request for quotation
CAS: 5927-18-4
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Email: Lucy@verypharm.com
Mobile: +86-13606544505
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Product Name: Trimethyl phosphonoacetate Request for quotation
CAS: 5927-18-4
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5927-18-4
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