59565-53-6
4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol
CAS: 59565-53-6
Molecular Formula: C8H7N3OS
59565-53-6 - Names and Identifiers
59565-53-6 - Physico-chemical Properties
| Molecular Formula | C8H7N3OS |
| Molar Mass | 193.23 |
| Density | 1.471±0.06 g/cm3(Predicted) |
| Melting Point | 320 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 435.0±47.0 °C(Predicted) |
| pKa | 8.26±0.15(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD03659018 |
59565-53-6 - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
59565-53-6 - Introduction
4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol, also known as 4-(5-amino-[1,3,4]thiadiazol-2-yl)-phenol, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White-light yellow crystalline powder
-Molecular formula: C7H6N4OS
-Molecular weight: 198.22g/mol
-Melting point: about 163-168°C
-Solubility: Soluble in many organic solvents (such as chloroform, methanol and dichloromethane)
Use:
- 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is a potential bioactive molecule with antibacterial, antiparasitic and antitumor activities.
-It is widely used in drug research and development in the pharmaceutical field.
Preparation Method:
The preparation method of 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is more complicated and can be synthesized by multi-step reaction. A more common preparation method is as follows:
1. Dissolve p-nitrophenol in concentrated ammonia.
2. Slowly add sulfuryl chloride at low temperature.
3. After the reaction proceeds, 4-(5-sulfuryl-[1,3,4] thiadiazol-2-yl)-phenol will be formed in the solution.
4. The intermediate is reacted with a reducing agent such as ammonia water to obtain the final product 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol.
Safety Information:
-Because 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is not widely used in industrial production, its detailed safety information and toxicity data may not have been fully studied and reported.
-During operation, appropriate safety precautions should be taken, such as gloves, protective glasses and protective clothing.
-If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: White-light yellow crystalline powder
-Molecular formula: C7H6N4OS
-Molecular weight: 198.22g/mol
-Melting point: about 163-168°C
-Solubility: Soluble in many organic solvents (such as chloroform, methanol and dichloromethane)
Use:
- 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is a potential bioactive molecule with antibacterial, antiparasitic and antitumor activities.
-It is widely used in drug research and development in the pharmaceutical field.
Preparation Method:
The preparation method of 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is more complicated and can be synthesized by multi-step reaction. A more common preparation method is as follows:
1. Dissolve p-nitrophenol in concentrated ammonia.
2. Slowly add sulfuryl chloride at low temperature.
3. After the reaction proceeds, 4-(5-sulfuryl-[1,3,4] thiadiazol-2-yl)-phenol will be formed in the solution.
4. The intermediate is reacted with a reducing agent such as ammonia water to obtain the final product 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol.
Safety Information:
-Because 4-(5-Amino-[1,3,4]thiadiazol-2-yl)-phenol is not widely used in industrial production, its detailed safety information and toxicity data may not have been fully studied and reported.
-During operation, appropriate safety precautions should be taken, such as gloves, protective glasses and protective clothing.
-If you come into contact with this substance, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 21:04:16
