6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline
CAS: 406463-06-7
Molecular Formula: C15H18BNO2
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline - Names and Identifiers
| Name | 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline |
| Synonyms | Quinoline-6-boronic acid picol ester Quinoline-6-boronic acid,pinacol ester 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline 2-(Quinolin-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Quinoline, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline, 6-Quinolylboronic acid pinacol ester |
| CAS | 406463-06-7 |
| InChI | InChI=1/C15H18BNO2/c1-14(2)15(3,4)19-16(18-14)12-7-8-13-11(10-12)6-5-9-17-13/h5-10H,1-4H3 |
| InChIKey | VMFALDWCEQUFSX-UHFFFAOYSA-N |
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline - Physico-chemical Properties
| Molecular Formula | C15H18BNO2 |
| Molar Mass | 255.12 |
| Density | 1.1g/cm3 |
| Melting Point | 62-66°C(lit.) |
| Boling Point | 386.5°C at 760 mmHg |
| Flash Point | 187.5°C |
| Vapor Presure | 7.86E-06mmHg at 25°C |
| Appearance | Powder or Crystalline Solid |
| Color | White to pale orange |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.558 |
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline - Introduction
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline is an organic compound with the chemical formula Con.
Nature:
-Appearance: white or off-white crystalline solid
-Melting point: about 115-117°C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and chloroform, insoluble in water
Use:
- 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline is widely used as a catalyst in organic synthesis.
-It can be used as a precursor of complex catalyst for asymmetric hydrogenation, aldehyde and reduction of other carbonyl compounds.
Preparation Method:
The preparation method of 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline mainly includes the following steps:
1. Reaction of 4,4,5,5-tetramethyl -1,3, 2-dioxoborane tricyclohexane and 6-bromoquinoline to obtain 4,4,5,5-tetramethyl -1,3, 2-dioxoborane tricyclohexan-6-yl-quinoline.
2. The above product was reduced using sodium hydroxide in methanol to obtain the desired 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline.
Safety Information:
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline has limited safety information. The following should be noted when using:
-Use appropriate personal protective equipment such as goggles, gloves and protective clothing during operation.
-Avoid inhalation, ingestion or contact with skin and eyes.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-Avoid contact with oxidants and strong acids.
Please note that the information provided above is for informational purposes only and does not represent an exhaustive description of the properties, uses, preparation and safety of the compounds. Before using this compound, it is recommended to refer to reliable chemical literature and safety data, and to follow appropriate laboratory safety regulations.
Nature:
-Appearance: white or off-white crystalline solid
-Melting point: about 115-117°C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide and chloroform, insoluble in water
Use:
- 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline is widely used as a catalyst in organic synthesis.
-It can be used as a precursor of complex catalyst for asymmetric hydrogenation, aldehyde and reduction of other carbonyl compounds.
Preparation Method:
The preparation method of 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline mainly includes the following steps:
1. Reaction of 4,4,5,5-tetramethyl -1,3, 2-dioxoborane tricyclohexane and 6-bromoquinoline to obtain 4,4,5,5-tetramethyl -1,3, 2-dioxoborane tricyclohexan-6-yl-quinoline.
2. The above product was reduced using sodium hydroxide in methanol to obtain the desired 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline.
Safety Information:
6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline has limited safety information. The following should be noted when using:
-Use appropriate personal protective equipment such as goggles, gloves and protective clothing during operation.
-Avoid inhalation, ingestion or contact with skin and eyes.
-Operate in a well-ventilated place to avoid inhaling its vapor.
-Avoid contact with oxidants and strong acids.
Please note that the information provided above is for informational purposes only and does not represent an exhaustive description of the properties, uses, preparation and safety of the compounds. Before using this compound, it is recommended to refer to reliable chemical literature and safety data, and to follow appropriate laboratory safety regulations.
Last Update：2024-04-10 22:29:15
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Product Name: 6-Quinolineboronic Acid Pinacol Ester Visit Supplier Webpage Request for quotation
CAS: 406463-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 406463-06-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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