6-(Naphthalen-1-ylmethylsulfanyl)-7H-purine
PU 02
CAS: 313984-77-9
Molecular Formula: C16H12N4S
6-(Naphthalen-1-ylmethylsulfanyl)-7H-purine - Names and Identifiers
6-(Naphthalen-1-ylmethylsulfanyl)-7H-purine - Physico-chemical Properties
| Molecular Formula | C16H12N4S |
| Molar Mass | 292.36 |
| Storage Condition | 2-8°C |
| MDL | MFCD23381174 |
6-(Naphthalen-1-ylmethylsulfanyl)-7H-purine - Reference Information
| biological activity | PU02 is a derivative of 6-MP (HY-13677) and a negative allosteric modulator of the 5-HT3 receptor, the IC50 values measured in HEK293 cells after transfection of 5-HT3A and 5-HT3AB receptors were 0.36 and 0.73 μm, respectively. |
| Cell Line: | HepG2 cells. |
| Concentration: | 6.26, 12.5, 25, 50 μM. |
| Incubation Time: | 6, 12, 24, 36 h. |
| Result: | Induced mitochondria-dependent apoptosis. |
Last Update：2024-04-09 21:11:58
