6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole

6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole - Names and Identifiers

Name	1-hydroxy-6-(trifluoromethyl)benzo-triazole
Synonyms	6-(TRIFLUORO-METHYL)-HOBT 6-TrifluoroMethyl-benzotriazol-1-ol 6-(trifluoromethyl)-1H-benzotriazol-1-ol 1-Hydro-6-(trifluoromethyl)benzotriazole 1-Hydroxy-6-trifluoromethylbenzotriazole 1-HYDROXY-6-(TRIFLUOROMETHYL)BENZOTRIAZO 1-hydroxy-6-(trifluoromethyl)benzotriazole 1-HYDROXY-6-(TRIFLUOROMETHYL)BENZOTRIAZOLE 1-hydroxy-6-(trifluoromethyl)benzo-triazole 1-Hydroxy-6-(trifluoromethyl)-1H-benzotriazole 6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole 6-(trifluoromethyl)-1H-benzo[d][1,2,3]triazol-1-ol
CAS	26198-21-0
InChI	InChI=1/C7H4F3N3O/c8-7(9,10)4-1-2-5-6(3-4)13(14)12-11-5/h1-3,14H

6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole - Physico-chemical Properties

Molecular Formula	C7H4F3N3O
Molar Mass	203.12
Density	1.69±0.1 g/cm3(Predicted)
Melting Point	143-145°C
Boling Point	328.6±52.0 °C(Predicted)
Flash Point	152.5°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	9.79E-05mmHg at 25°C
Appearance	Solid
Color	White to Light Yellow
Maximum wavelength(λmax)	['362nm(lit.)']
pKa	6.77±0.58(Predicted)
Storage Condition	Store at RT.
Stability	Possibly Shock Sensitive
Refractive Index	1.595

6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R5 - Heating may cause an explosion R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 1325 4.1/PG II
Hazard Class	4.1
Packing Group	II

6-(Trifluoromethyl)-1-hydroxy-1H-benzotriazole - Introduction

1-hydroxy-6-(trifluoromethyl)benzo-triazole is an organic compound with the chemical formula C8H5F3N4O.

Nature:
1-hydroxy-6-(trifluoromethyl)benzo-triazole is a white crystalline solid with the characteristics of benzotriazole compounds. It is stable at room temperature, but may produce toxic gases at high temperatures and fire sources.

Use:
1-hydroxy-6-(trifluoromethyl) is benzo-triazole used in the synthesis of cis-trans isomers of dyes in the pigment and dye industry, and can also be used in coupling reactions and catalytic reactions in organic synthesis.

Method:
1-hydroxy-6-(trifluoromethyl)benzo-triazole are generally prepared by chemical reaction of benzotriazole. One of the commonly used methods is the reaction of benzotriazole with trifluoromethyl acid followed by hydroxylation.

Safety Information:
1-hydroxy-6-(trifluoromethyl)benzo-triazole are generally stable and relatively safe under normal conditions of use. However, it may be irritating to the eyes, skin and respiratory tract, so appropriate protective measures should be taken during operation, such as wearing protective glasses, gloves and respirators. In addition, should be away from fire and high temperature environment, avoid contact with strong oxidants. If inhaled or ingested by mistake, seek medical attention immediately.

Last Update：2024-04-10 22:29:15