6-Bromo-2-hydroxy-4-(trifluoromethyl)quinolin
6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one
CAS: 328955-61-9
Molecular Formula: C10H5BrF3NO
6-Bromo-2-hydroxy-4-(trifluoromethyl)quinolin - Names and Identifiers
6-Bromo-2-hydroxy-4-(trifluoromethyl)quinolin - Physico-chemical Properties
| Molecular Formula | C10H5BrF3NO |
| Molar Mass | 292.05 |
| Density | 1.724±0.06 g/cm3(Predicted) |
| Melting Point | 227℃ (sublm) |
| Boling Point | 333.1±42.0 °C(Predicted) |
| pKa | 9.50±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD11846359 |
6-Bromo-2-hydroxy-4-(trifluoromethyl)quinolin - Introduction
6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one is an organic compound with the formula C10H5BrF3NO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one is a white crystalline solid.
-Melting point: about 172-176 degrees Celsius.
-Soluble: Soluble in organic solvents, such as chloroform, dichloromethane and ether.
Use:
6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one has several potential uses in the medical field, particularly in pharmaceutical research and development. It may have antiviral, antifungal and antitumor activities. In addition, it can also be used as a starting material in organic synthesis, such as a reagent or an intermediate in a chemical reaction.
Preparation Method:
A commonly used preparation method is to react 4-(trifluoromethyl)-6-bromoquinoline with trifluoroformic acid to obtain 4-(trifluoromethyl)-6-bromoquinoline. Next, this compound is subjected to an oxidation reaction with a base to produce 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one.
Safety Information:
General chemical safety procedures should be followed when handling 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one. It may be irritating to the skin and eyes, please avoid contact. Wear appropriate personal protective equipment, such as lab gloves and goggles, to ensure safety. In addition, the toxicity and biological activity of the compound need to be further studied. In laboratory and industrial production, relevant safety regulations and operating standards should be observed.
Nature:
-Appearance: 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one is a white crystalline solid.
-Melting point: about 172-176 degrees Celsius.
-Soluble: Soluble in organic solvents, such as chloroform, dichloromethane and ether.
Use:
6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one has several potential uses in the medical field, particularly in pharmaceutical research and development. It may have antiviral, antifungal and antitumor activities. In addition, it can also be used as a starting material in organic synthesis, such as a reagent or an intermediate in a chemical reaction.
Preparation Method:
A commonly used preparation method is to react 4-(trifluoromethyl)-6-bromoquinoline with trifluoroformic acid to obtain 4-(trifluoromethyl)-6-bromoquinoline. Next, this compound is subjected to an oxidation reaction with a base to produce 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one.
Safety Information:
General chemical safety procedures should be followed when handling 6-Bromo-4-(trifluoromethyl)quinolin-2(1H)-one. It may be irritating to the skin and eyes, please avoid contact. Wear appropriate personal protective equipment, such as lab gloves and goggles, to ensure safety. In addition, the toxicity and biological activity of the compound need to be further studied. In laboratory and industrial production, relevant safety regulations and operating standards should be observed.
Last Update：2024-04-09 20:52:54
