6-Bromo-3-methylpyrazine-2-carboxylate
6-Bromo-2-pyrazinecarboxylic acid methyl ester
CAS: 40155-34-8
Molecular Formula: C6H5BrN2O2
6-Bromo-3-methylpyrazine-2-carboxylate - Names and Identifiers
6-Bromo-3-methylpyrazine-2-carboxylate - Physico-chemical Properties
| Molecular Formula | C6H5BrN2O2 |
| Molar Mass | 217.02 |
| Density | 1.669±0.06 g/cm3 (20 ºC 760 Torr) |
| Boling Point | 268.6±35.0℃ (760 Torr) |
| Flash Point | 116.3±25.9℃ |
| pKa | -2.36±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD14155890 |
6-Bromo-3-methylpyrazine-2-carboxylate - Introduction
Acid methyl ester is an organic compound that contains a 6-bromo-2-pyrazinyl group and a methyl ester group in its chemical structure. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C7H6BrN2O2
-Molecular weight: 218.04g/mol
-Melting point: 116-118°C
-Boiling Point: 295-297°C
-Solubility: Soluble in some organic solvents, such as methanol, ethanol and dichloromethane
Use:
-or acid methyl ester can be used as an intermediate or reagent in organic synthesis for the synthesis of other compounds.
-It can be used in the fields of drug synthesis, pesticide synthesis and chemical research.
Preparation Method:
-The preparation of acid methyl ester can be carried out by the following steps:
1. Suspend methyl 2-pyrazinecarboxylate in dichloromethane.
2. Add sodium bromide and stir the reaction mixture.
3. Stir the reaction mixture at room temperature for about 4 hours.
4. The reaction mixture was filtered and then subjected to crystal crystallization.
5. The crystals are collected and dried to finally obtain the acid methyl ester product.
Safety Information:
-acid methyl ester may cause irritation when in contact with skin, eyes and mucous membranes. Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-During use or storage, avoid contact with oxidants and strong bases/acids to avoid dangerous chemical reactions.
-It should be operated in a well-ventilated environment to avoid inhaling its vapor or dust.
-If you accidentally come into contact with this compound, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C7H6BrN2O2
-Molecular weight: 218.04g/mol
-Melting point: 116-118°C
-Boiling Point: 295-297°C
-Solubility: Soluble in some organic solvents, such as methanol, ethanol and dichloromethane
Use:
-or acid methyl ester can be used as an intermediate or reagent in organic synthesis for the synthesis of other compounds.
-It can be used in the fields of drug synthesis, pesticide synthesis and chemical research.
Preparation Method:
-The preparation of acid methyl ester can be carried out by the following steps:
1. Suspend methyl 2-pyrazinecarboxylate in dichloromethane.
2. Add sodium bromide and stir the reaction mixture.
3. Stir the reaction mixture at room temperature for about 4 hours.
4. The reaction mixture was filtered and then subjected to crystal crystallization.
5. The crystals are collected and dried to finally obtain the acid methyl ester product.
Safety Information:
-acid methyl ester may cause irritation when in contact with skin, eyes and mucous membranes. Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-During use or storage, avoid contact with oxidants and strong bases/acids to avoid dangerous chemical reactions.
-It should be operated in a well-ventilated environment to avoid inhaling its vapor or dust.
-If you accidentally come into contact with this compound, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:57
