6-Bromo-3-methylquinazolin-4(3H)-one

6-Bromo-3-methylquinazolin-4(3H)-one - Names and Identifiers

Name	6-bromo-3-methylquinazolin-4(3H)-one
Synonyms	6-BROMO-3-METHYL-4-QUINAZOLINONE 6-BroMo-3-Methyl-3H-quinazolin-4-one 6-bromo-3-methylquinazolin-4(3H)-one 6-Bromo-3-methylquinazolin-4(3H)-one 4(3H)-Quinazolinone, 6-bromo-3-methyl-
CAS	57573-59-8
EINECS	200-589-5
InChI	InChI=1/C9H7BrN2O/c1-12-5-11-8-3-2-6(10)4-7(8)9(12)13/h2-5H,1H3

6-Bromo-3-methylquinazolin-4(3H)-one - Physico-chemical Properties

Molecular Formula	C9H7BrN2O
Molar Mass	239.07
Density	1.65±0.1 g/cm3(Predicted)
Boling Point	364.2±44.0 °C(Predicted)
Flash Point	174°C
Vapor Presure	1.71E-05mmHg at 25°C
pKa	0.90±0.70(Predicted)
Storage Condition	2-8°C
Refractive Index	1.67

6-Bromo-3-methylquinazolin-4(3H)-one - Introduction

(3H)-one is an organic compound with the chemical formula C10H7BrN2O.

Nature:
-Appearance: White crystalline solid
-Melting point: about 160-162°C
-Solubility: It has certain solubility in common organic solvents such as chloroform and dichloromethane.

Use:
(3H)-one is an important intermediate compound commonly used in organic synthesis reactions. For example, it can be used as a starting material for drug synthesis, pesticide synthesis and dye synthesis.

Preparation Method:
(3H)-one can be synthesized by the following steps:
1. 3-bromo-5-methylquinazoline and bromoketone sodium were reacted in an organic solvent to give 6-bromo-3-methylquinazoline.
2. react 6-bromo-3-methyl quinazoline with ammonia and cyanogen chloride in an organic solvent to obtain (3H)-one.

Safety Information:
During use and storage, it is necessary to follow appropriate safety procedures, such as wearing appropriate protective equipment (such as gloves and glasses) to avoid contact with skin and eyes. In addition, the toxicity information of this compound is limited, so please handle it with caution.

Last Update：2024-04-09 20:52:54