6-Bromo-5-chloro-1H-indole - Names and Identifiers
6-Bromo-5-chloro-1H-indole - Physico-chemical Properties
Molecular Formula | C8H5BrClN
|
Molar Mass | 230.49 |
Density | 1.772 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | IRRITANT |
MDL | MFCD11848570 |
6-Bromo-5-chloro-1H-indole - Introduction
6-Bromo-5-chloro-1H-indole is an organic compound with the chemical formula C≡H∞BrClN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 6-Bromo-5-chloro-1H-indole is a colorless to pale yellow crystalline solid.
-Melting point: approximately 140-142°C.
-Solubility: It has good solubility in some organic solvents such as ethanol and dimethyl sulfoxide, but it has poor solubility in water.
Use:
-Chemical reagents: 6-Bromo-5-chloro-1H-indole can be used as an important intermediate for the synthesis of other organic compounds.
-Drug research: It has certain applications in drug research and can be used to synthesize and study potential biologically active substances.
Preparation Method:
The preparation of 6-bromo-5-chloro-1H-indole can be carried out by the following steps:
1. Dissolve indole in dimethyl sulfoxide.
2. Slowly add ferrous oxide (III) or manganese dioxide at a ratio of 1:1.
3. Heat until the reaction solution boils. After the reaction is completed, the precipitate is cooled and filtered.
4. Further purification and crystallization to obtain the desired product.
Safety Information:
-6-Bromo-5-chloro-1H-indole is a chemical that requires proper protective equipment such as glasses, gloves, and lab coats.
-Avoid inhalation or skin contact, avoid ingestion, should be away from children and pets.
-Waste should be disposed of properly in accordance with local regulations.
Please note that the information provided here is based on general information, and specific chemicals should be judged based on their specific chemical properties and uses. Before using or handling any chemical, it is recommended to consult the exact Safety Data Sheet (SDS) and follow the relevant safe operating procedures.
Last Update:2024-04-09 15:17:51