6-Bromo-7-fluoroquinoline
6-bromo-7-fluoroquinoline
CAS: 127827-52-5
Molecular Formula: C9H5BrFN
6-Bromo-7-fluoroquinoline - Names and Identifiers
| Name | 6-bromo-7-fluoroquinoline |
| Synonyms | 6-Bromo-7-fluoroquinoline 6-bromo-7-fluoroquinoline Quinoline, 6-bromo-7-fluoro- |
| CAS | 127827-52-5 |
| EINECS | 817-368-0 |
| InChI | InChI=1S/C9H5BrFN/c10-7-4-6-2-1-3-12-9(6)5-8(7)11/h1-5H |
6-Bromo-7-fluoroquinoline - Physico-chemical Properties
| Molecular Formula | C9H5BrFN |
| Molar Mass | 226.05 |
| Density | 1.647±0.06 g/cm3(Predicted) |
| Boling Point | 295.7±20.0 °C(Predicted) |
| Flash Point | 132.628 °C |
| pKa | 3.01±0.17(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
6-Bromo-7-fluoroquinoline - Introduction
6-bromo-7-fluoroquinoline is an organic compound with the chemical formula C9H5BrFN. It is a white crystal with a fragrant smell. The following is a description of the properties, uses, preparation and safety information of 6-bromo-7-fluoroquinoline:
Nature:
-Appearance: White crystal
-Molecular weight: 220.04g/mol
-Melting point: 65-67°C
-Boiling point: 260°C
-Density: 1.69g/cm³
-Solubility: Soluble in chloroform, ethanol, acetone and dichloromethane, insoluble in water
Use:
6-bromo-7-fluoroquinoline is commonly used in the synthesis of pesticides and can be used in the formulation of insecticides, fungicides and herbicides.
Preparation Method:
6-Bromo-7-fluoroquinoline can be synthesized by the following steps:
1. with 6-chloro-7-fluoroquinoline as the starting material, it reacts with potassium bromide in ammonia solution to generate 6-bromo-7-chloroquinoline.
2. 6-bromo-7-chloroquinoline is reacted with silver fluoride in dichloromethane to obtain 6-bromo-7-fluoroquinoline.
Safety Information:
6-Bromo-7-fluoroquinoline requires care during handling and use, and the following safety measures must be observed:
-Must operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, safety glasses and protective clothing.
-Avoid contact with skin, eyes or respiratory tract. If there is contact, rinse immediately with plenty of water and seek medical advice.
-Store away from fire and oxidant, keep sealed to prevent contact with moisture in the air.
-After use and disposal, the work area should be thoroughly cleaned and relevant waste disposal regulations should be followed.
Nature:
-Appearance: White crystal
-Molecular weight: 220.04g/mol
-Melting point: 65-67°C
-Boiling point: 260°C
-Density: 1.69g/cm³
-Solubility: Soluble in chloroform, ethanol, acetone and dichloromethane, insoluble in water
Use:
6-bromo-7-fluoroquinoline is commonly used in the synthesis of pesticides and can be used in the formulation of insecticides, fungicides and herbicides.
Preparation Method:
6-Bromo-7-fluoroquinoline can be synthesized by the following steps:
1. with 6-chloro-7-fluoroquinoline as the starting material, it reacts with potassium bromide in ammonia solution to generate 6-bromo-7-chloroquinoline.
2. 6-bromo-7-chloroquinoline is reacted with silver fluoride in dichloromethane to obtain 6-bromo-7-fluoroquinoline.
Safety Information:
6-Bromo-7-fluoroquinoline requires care during handling and use, and the following safety measures must be observed:
-Must operate in a well-ventilated area and wear appropriate personal protective equipment, such as gloves, safety glasses and protective clothing.
-Avoid contact with skin, eyes or respiratory tract. If there is contact, rinse immediately with plenty of water and seek medical advice.
-Store away from fire and oxidant, keep sealed to prevent contact with moisture in the air.
-After use and disposal, the work area should be thoroughly cleaned and relevant waste disposal regulations should be followed.
Last Update：2024-04-10 22:29:15
