6-Bromopyridin-2(1H)-one
2-Bromo-6-hydroxypyridine
CAS: 27992-32-1
Molecular Formula: C5H4BrNO
6-Bromopyridin-2(1H)-one - Names and Identifiers
| Name | 2-Bromo-6-hydroxypyridine |
| Synonyms | 6-Bromo-2-pyridone 2-Bromo-6-pyridinol 6-Bromopyridin-2-ol 6-BROMOPYRIDIN-2-OL 6-Bromopyridine-2-ol 6-Bromopyridin-2(1H)-one 6-bromopyridin-2(1H)-one 2-BROMO-6-HYDROXYPYRIDINE 6-Bromo-2-hydroxypyridine 2-Bromo-6-hydroxypyridine |
| CAS | 27992-32-1 |
| EINECS | 807-967-5 |
| InChI | InChI=1/C5H4BrNO/c6-4-2-1-3-5(8)7-4/h1-3H,(H,7,8) |
6-Bromopyridin-2(1H)-one - Physico-chemical Properties
| Molecular Formula | C5H4BrNO |
| Molar Mass | 174 |
| Density | 1.776±0.06 g/cm3(Predicted) |
| Melting Point | 121.0 to 125.0 °C |
| Boling Point | 336.6±42.0 °C(Predicted) |
| Flash Point | 157.4°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.000111mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Light yellow to Purple |
| pKa | 7.33±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.6 |
| MDL | MFCD00234043 |
6-Bromopyridin-2(1H)-one - Introduction
2-Bromo-6-hydroxypyridine is an organic compound with the chemical formula C5H4BrNO.
Nature:
-Appearance: Colorless or light yellow crystal
-Melting Point: 94-98 ℃
-Boiling point: 232-233 ℃
-Density: 1.646g/cm³
-Solubility: Soluble in alcohols, ethers and chlorinated hydrocarbons, slightly soluble in water
Use:
- 2-Bromo-6-hydroxypyridine can be used as a starting material for organic synthesis and used to prepare other compounds, such as drugs, pesticides, dyes, etc.
Method:
-2-Bromo-6-hydroxypyridine is obtained by the reaction of 2-pyridinecarboxaldehyde and carbon tetrachloride.
-Specific steps:
1. Dissolve 2-pyridine formaldehyde with carbon tetrachloride
2. Adding cuprous bromide and N-bromosuccinimide to react to generate 2-Bromo-6-hydroxypyridine
3. Filtration, crystallization, washing to obtain the product
4. Drying to obtain 2-Bromo-6-hydroxypyridine Crystal
Safety Information:
- 2-Bromo-6-hydroxypyridine is an organic compound with a certain degree of danger.
-May cause eye, skin and respiratory tract irritation.
-During operation, it is recommended to wear personal protective equipment, such as laboratory gloves, goggles, etc.
-storage should be sealed, away from fire, heat and oxidant.
Nature:
-Appearance: Colorless or light yellow crystal
-Melting Point: 94-98 ℃
-Boiling point: 232-233 ℃
-Density: 1.646g/cm³
-Solubility: Soluble in alcohols, ethers and chlorinated hydrocarbons, slightly soluble in water
Use:
- 2-Bromo-6-hydroxypyridine can be used as a starting material for organic synthesis and used to prepare other compounds, such as drugs, pesticides, dyes, etc.
Method:
-2-Bromo-6-hydroxypyridine is obtained by the reaction of 2-pyridinecarboxaldehyde and carbon tetrachloride.
-Specific steps:
1. Dissolve 2-pyridine formaldehyde with carbon tetrachloride
2. Adding cuprous bromide and N-bromosuccinimide to react to generate 2-Bromo-6-hydroxypyridine
3. Filtration, crystallization, washing to obtain the product
4. Drying to obtain 2-Bromo-6-hydroxypyridine Crystal
Safety Information:
- 2-Bromo-6-hydroxypyridine is an organic compound with a certain degree of danger.
-May cause eye, skin and respiratory tract irritation.
-During operation, it is recommended to wear personal protective equipment, such as laboratory gloves, goggles, etc.
-storage should be sealed, away from fire, heat and oxidant.
Last Update：2024-04-09 15:17:56
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