6-CHLOROQUINALDINE
6-Chloro-2-methylquinoline
CAS: 92-46-6
Molecular Formula: C10H8ClN
6-CHLOROQUINALDINE - Names and Identifiers
| Name | 6-Chloro-2-methylquinoline |
| Synonyms | 6-CHLOROQUINALDINE 6-Chloroquinaldine 6-Chloro-2-methylquinoline 2-Methyl-6-chloroquinoline 6-CHLORO-2-METHYLQUINOLINE Quinoline, 6-chloro-2-methyl- |
| CAS | 92-46-6 |
| EINECS | 626-187-4 |
| InChI | InChI=1/C10H8ClN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h2-6H,1H3 |
6-CHLOROQUINALDINE - Physico-chemical Properties
| Molecular Formula | C10H8ClN |
| Molar Mass | 177.63 |
| Density | 1.225±0.06 g/cm3(Predicted) |
| Melting Point | 94-98 °C (lit.) |
| Boling Point | 278.2±20.0 °C(Predicted) |
| Flash Point | 148.7°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.00732mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Light yellow |
| pKa | 5.02±0.43(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.634 |
6-CHLOROQUINALDINE - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
6-CHLOROQUINALDINE - Introduction
6-Chloro-2-methylquinoline is an organic compound with the formula C10H8ClN, which is a heterocyclic compound. The following is a description of some properties, uses, methods and safety information of 6-Chloro-2-methylquinoline:
Nature:
-Appearance: 6-Chloro-2-methylquinoline is a pale yellow solid.
-Melting point: Its melting point is 74-77°C.
-Boiling point: It sublimes in the range of about 330-340°C.
-Solubility: 6-Chloro-2-methylquinoline has a certain solubility in non-polar solvents (such as ethanol, dimethylformamide, etc.).
Use:
-Chemical synthesis: 6-Chloro-2-methylquinoline can be used to synthesize other organic compounds, such as the preparation of pyran and thiophene derivatives.
-Drug research: It is also used as an intermediate in drug research and has certain application potential in the field of drug development.
Method:
6-Chloro-2-methylquinoline can be prepared by the following method:
1. benzoyl chloride and 3-amino methyl pyridine reaction, and then chlorination reaction.
2. Sodium borohydride was added to a solution of 6-chloroquinoline to perform a reduction reaction to obtain 6-Chloro-2-methylquinoline.
Safety Information:
As a chemical, 6-Chloro-2-methylquinoline is dangerous and requires attention to the following safety issues:
-Wear appropriate protective equipment such as gloves and safety glasses when using.
-Avoid inhalation or contact with skin and eyes.
-Use in a well-ventilated place, away from fire sources and open flames.
-Avoid contact with oxidants and strong acids during storage.
-Comply with the relevant dangerous goods regulations when using or handling the compound, and use correct chemical laboratory operation methods.
Nature:
-Appearance: 6-Chloro-2-methylquinoline is a pale yellow solid.
-Melting point: Its melting point is 74-77°C.
-Boiling point: It sublimes in the range of about 330-340°C.
-Solubility: 6-Chloro-2-methylquinoline has a certain solubility in non-polar solvents (such as ethanol, dimethylformamide, etc.).
Use:
-Chemical synthesis: 6-Chloro-2-methylquinoline can be used to synthesize other organic compounds, such as the preparation of pyran and thiophene derivatives.
-Drug research: It is also used as an intermediate in drug research and has certain application potential in the field of drug development.
Method:
6-Chloro-2-methylquinoline can be prepared by the following method:
1. benzoyl chloride and 3-amino methyl pyridine reaction, and then chlorination reaction.
2. Sodium borohydride was added to a solution of 6-chloroquinoline to perform a reduction reaction to obtain 6-Chloro-2-methylquinoline.
Safety Information:
As a chemical, 6-Chloro-2-methylquinoline is dangerous and requires attention to the following safety issues:
-Wear appropriate protective equipment such as gloves and safety glasses when using.
-Avoid inhalation or contact with skin and eyes.
-Use in a well-ventilated place, away from fire sources and open flames.
-Avoid contact with oxidants and strong acids during storage.
-Comply with the relevant dangerous goods regulations when using or handling the compound, and use correct chemical laboratory operation methods.
Last Update：2024-04-09 19:05:52
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QQ: 3008007409
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