Name | 2-Chloro-5-Hydroxypyridine |
Synonyms | 2-Chloro-5-Pyridol 6-chloropyridin-3-ol 2-Chloro-5-pyridinol 6-CHLOROPYRIDIN-3-OL 2-CHLORO-5-PYRIDINOL 2-Chloropyridin-5-ol 6-Chloro-3-pyridinol 6-Chloropyridin-3-ol 3-PYRIDINOL, 6-CHLORO- 2-Chloro-5-Hydroxypyridine 3-Pyridinol,6-chloro-(9CI) 2-CHLORO-5-HYDROXYPYRIDINE |
CAS | 41288-96-4 |
EINECS | 670-289-1 |
InChI | InChI=1/C5H4ClNO/c6-5-2-1-4(8)3-7-5/h1-3,8H |
Molecular Formula | C5H4ClNO |
Molar Mass | 129.54 |
Density | 1.392±0.06 g/cm3(Predicted) |
Melting Point | 155-158°C |
Boling Point | 351.9±22.0 °C(Predicted) |
Flash Point | 166.6°C |
Vapor Presure | 1.97E-05mmHg at 25°C |
Appearance | Bright yellow crystal |
Color | Light yellow to Brown |
pKa | 8.69±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.583 |
MDL | MFCD00234050 |
Physical and Chemical Properties | Light yellow crystal |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S37 - Wear suitable gloves. |
HS Code | 29333990 |
Hazard Class | IRRITANT |
Packing Group | III |
Use | 2-chloro-5-hydroxypyridine is an organic intermediate. |
Synthesis | 2-chloro-5-hydroxypyridine can be diazotized from 2-amino-5-bromopyridine to prepare 5-bromo-2-chloropyridine, Then prepare 2-chloro-5-pyridine boric acid, and finally hydrolyze to obtain 2-chloro-5-hydroxypyridine. |