6-Chloro-5-Methylpyridine-3-carboxaldehyde

6-Chloro-5-Methylpyridine-3-carboxaldehyde - Names and Identifiers

Name	3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-
Synonyms	6-Chloro-5-methylnicotinaldehyde 2-Chloro-5-formyl-3-methylpyridine 6-Chloro-3-formyl-5-methylpyridine 6-CHLORO-5-METHYLPYRIDINE-3-CARBALDEHYDE 6-Chloro-5-Methylpyridine-3-Carbaldehyde 6-Chloro-5-Methylpyridine-3-carboxaldehyde 6-chloro-5-methyl-3-pyridinecarboxaldehyde 6-Chloro-5-methylpyridine-3-carboxaldehyde 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl- 6-Chloro-5-methylpyridine-3-carboxaldehyde, 2-Chloro-5-formyl-3-methylpyridine
CAS	176433-43-5

6-Chloro-5-Methylpyridine-3-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C7H6ClNO
Molar Mass	155.58
Density	1.269±0.06 g/cm3(Predicted)
Melting Point	51-53°
Boling Point	269.2±35.0 °C(Predicted)
pKa	-1.24±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

6-Chloro-5-Methylpyridine-3-carboxaldehyde - Risk and Safety

Hazard Class

IRRITANT

6-Chloro-5-Methylpyridine-3-carboxaldehyde - Introduction

3-Pyridinecarboxaldehyde, 6-choro-5-methyll-, chemical formula C7H5ClNO2, molecular weight of 171.57g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: 3-Pyridinecarboxaldehyde, 6-chroo-5-methyl-is a colorless crystalline solid.
2. Melting point: About 120°C to 122°C.
3. Boiling point: About 335 ℃.
4. Insoluble in water, but soluble in organic solvents such as ether and alcohol solvents.

Use:
1. 3-Pyridinecarboxaldehyde, 6-choro-5-methyl-can be used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
2. In the field of pharmaceutical chemistry, the compound can be used to synthesize pyrrolidine phenols, which have anti-inflammatory, antibacterial and anti-tumor activities.

Method:
The synthesis method of 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-is generally as follows:
1. Dissolve 5-methyl pyridine-3-carboxaldehyde in an ethanol solution of cuprous chloride (CuCl2).
2. Add aluminum chloride (AlCl3) solution Dropwise at low temperature, and the reaction generates 3-Pyridinecarboxaldehyde, 6-chloro-5-methyll-.
3. The mixture was filtered to give the product as a solid.

Safety Information:
1. 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-may be irritating to eyes, skin and respiratory tract, please avoid direct contact.
2. During Operation should wear protective gloves, protective glasses and respiratory protection equipment.
3. If accidentally come into contact with the substance, should immediately rinse with plenty of water, and medical treatment.
4. The compound should be stored in a dry, cool, well-ventilated place, away from fire and oxidizing agents.
5. When disposing of waste, please comply with local environmental regulations and dispose of it in accordance with correct waste disposal methods.

Last Update：2024-04-09 02:00:43