6-Chloro-5-Methylpyrimidin-4-Amine

6-Chloro-5-Methylpyrimidin-4-Amine - Names and Identifiers

Name	4-Pyrimidinamine, 6-chloro-5-methyl-
Synonyms	6-chloro-5-methylpyrimidin-4-amine 6-Chloro-5-methyl-4-pyrimidinamine 6-Chloro-5-Methylpyrimidin-4-Amine 4-Amino-6-Chloro-5-Methylpyrimidine 6-AMINO-4-CHLORO-5-METHYLPYRIMIDINE 4-Pyrimidinamine, 6-Chloro-5-Methyl 4-Amino-6-chloro-5-methylpyrimidine 6-Amino-4-Chloro-5-Methylpyrimidine 4-Pyrimidinamine, 6-chloro-5-methyl- 6-Chloro-5-methyl-pyrimidin-4-ylamine 4-Pyrimidinamine, 6-chloro-5-methyl- (9CI)
CAS	14394-56-0
InChI	InChI=1/C5H6ClN3/c1-3-4(6)8-2-9-5(3)7/h2H,1H3,(H2,7,8,9)

6-Chloro-5-Methylpyrimidin-4-Amine - Physico-chemical Properties

Molecular Formula	C5H6ClN3
Molar Mass	143.57
Density	1.349±0.06 g/cm3(Predicted)
Melting Point	237-238℃
Boling Point	292.4±35.0 °C(Predicted)
Flash Point	130.613°C
Vapor Presure	0.002mmHg at 25°C
pKa	2.41±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.6

6-Chloro-5-Methylpyrimidin-4-Amine - Introduction

4-Pyrimidinamine, 6-chloro-5-methyl-is an organic compound with the chemical formula C5H5ClN4. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-Pyrimidinamine, 6-chloro-5-methyl-is a colorless crystalline solid.
-Melting point: About 270-273 degrees Celsius.
-Solubility: low solubility in water, better solubility in organic solvents.

Use:
- 4-Pyrimidinamine, 6-chloro-5-methyl-is mainly used for the preparation of other organic synthetic compounds, such as certain drugs, color dyes and pesticides.
-It is also used as a structurally observable marker for DNA bases.

Method:
- 4-Pyrimidinamine, 6-chloro-5-methyl-can be obtained by chlorination of 5-methyl-6-aminopyrimidine. First, 5-methyl-6-aminopyrimidine and hydrogen chloride are reacted under appropriate conditions to produce 4-Pyrimidinamine, 6-chloro-5-methyll-.

Safety Information:
- 4-Pyrimidinamine, 6-chloro-5-methyl-need to be stored properly, avoid direct sunlight and humid environment.
-In handling and use, must comply with the safety practice, wear appropriate personal protective equipment, such as glasses, gloves and laboratory coat, to avoid skin contact and inhalation.
-After contact with the substance, rinse immediately with plenty of water and seek medical assistance.
-When performing laboratory operations, ensure that the room is well ventilated and avoid inhaling toxic gases or vapors. This ensures safety and health and avoids accidents.

Last Update：2024-04-09 21:01:54