6-Fluoro-5-methylnicotinaldehyde - Names and Identifiers
6-Fluoro-5-methylnicotinaldehyde - Physico-chemical Properties
Molecular Formula | C7H6FNO
|
Molar Mass | 139.13 |
Density | 1.211 |
Boling Point | 249℃ |
Flash Point | 104℃ |
Vapor Presure | 0.0242mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.538 |
6-Fluoro-5-methylnicotinaldehyde - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
6-Fluoro-5-methylnicotinaldehyde - Introduction
It is an organic compound with a molecular formula of C7H6FNO and a structural formula:
It is a yellow solid with a unique smell. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Yellow solid
-Solubility: It can be dissolved in organic solvents such as alcohols and ketones, and its solubility in water is low.
-Melting point: about 46-48 ℃
-Boiling point: about 234-236 ℃
-Density: approx. 1.245g/cm3
Use:
It has many applications in organic synthesis, mainly for the preparation of drugs and chemical reagents. It can be used as an intermediate for the synthesis of a variety of drugs and active compounds, and is widely used in the field of pharmaceutical research and chemistry.
Preparation Method:
The preparation method of
can be obtained by the reaction of pyridine and formyl fluoride. The specific steps are as follows:
1. Pyridine was added to an appropriate amount of solvent and heated to reflux.
2. slowly add the formyl fluoride and maintain the temperature of the reaction system.
3. After several hours of reaction, after the end of the reaction, the product is obtained by distillation and crystallization.
Safety Information:
-is an organic compound, which is potentially dangerous.
-During use, appropriate protective measures, such as wearing suitable protective gloves, masks and protective glasses, are required.
-Avoid inhalation of gas, contact with skin, or ingestion.
-Storage should avoid contact with oxidants, strong acids and strong bases, and placed in a cool, dry place.
Please note that the above information is for reference only. For specific applications and more detailed safety information, it is recommended to refer to relevant literature or consult professionals.
Last Update:2024-04-09 15:18:00