6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline

6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline - Names and Identifiers

Name	2-Iodo-5-trifluoromethylpyridine
Synonyms	2-Iodo-5-(Trifluoromethyl)Pyri 2-Iodo-5-trifluoromethylpyridine 5-(trifluoromethyl)-2-iodopyridine 2-Iodo-5-(trifluoromethyl)pyridine Pyridine,2-iodo-5-(trifluoroMethyl)- 6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline
CAS	100366-75-4
InChI	InChI=1/C6H3F3IN/c7-6(8,9)4-1-2-5(10)11-3-4/h1-3H

6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline - Physico-chemical Properties

Molecular Formula	C6H3F3IN
Molar Mass	272.99
Density	1.974±0.06 g/cm3(Predicted)
Melting Point	82-83 °C(Solv: hexane (110-54-3))
Boling Point	215.7±40.0 °C(Predicted)
Flash Point	84.266°C
Vapor Presure	0.213mmHg at 25°C
pKa	-0.58±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Sensitive	Light Sensitive
Refractive Index	1.523

6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline - Risk and Safety

Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2811
WGK Germany	3
Hazard Class	IRRITANT
Packing Group	Ⅲ

6-Iodo-alpha,alpha,alpha-trifluoro-3-picoline - Introduction

2-iodo-5-trifluoromethylpyridine, chemical formula C6H2F3IN, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow solid
-melting point: 68-70 ℃
-Boiling point: 172-174 ℃
-Solubility: Soluble in organic solvents, such as methanol, ethanol, dichloromethane, etc.

Use:
2-iodo-5-trifluoromethylpyridine is commonly used as a reagent in organic synthesis. It has strong fluorinating agent properties and can be used as a catalyst or intermediate for fluorination reactions. It can also be used as a raw material in the pharmaceutical field and as an intermediate for the synthesis of some drugs.

Preparation Method:
2-iodine -5-trifluoromethylpyridine preparation methods are mainly the following:
-5-fluoro-2-trifluoromethylpyridine by iodide: 5-fluoro-2-trifluoromethylpyridine is reacted with iodine, and the target product is produced under the action of a catalyst.
-2-amino-5-trifluoromethylpyridine by iodide: 2-amino-5-trifluoromethylpyridine is reacted with iodine to obtain 2-iodo-5-trifluoromethylpyridine.

Safety Information:
2-iodo-5-trifluoromethylpyridine is a chemical, and the following safety precautions should be paid attention to when using it:
-The compound can be irritating to the eyes, skin and respiratory tract, and should be used to avoid contact.
-It is recommended to wear appropriate personal protective equipment, such as protective glasses, protective gloves and protective face mask, during use or operation.
-Avoid contact with fire and high temperature to avoid fire or explosion.
-stored should be sealed, away from light, low temperature, dry, away from flammables and oxidants.
-Proper laboratory practices and safety practices should be followed when using, storing or handling the compound.

Last Update：2024-04-09 15:17:50