Molecular Formula | C16H12O2 |
Molar Mass | 236.27 |
Density | 1.208±0.06 g/cm3(Predicted) |
Melting Point | 119-122°C (dec.)(lit.) |
Boling Point | 235°C/12mmHg(lit.) |
Storage Condition | Room Temprature |
In vitro study | 6-Methylflavone is an activator of α 1 β 2 γ 2L and α 1 β 2 GABA A receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α 1 β 2 γ 2L and α 1 β 2 GABA A receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC 50 at α 1 β 2 γ 2L GABA A receptors by 33±5.4%. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
Biological activity | 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. |
target | α 1 β 2 γ 2L GABA A receptor, α 1 β 2 GABA A receptor |
in vitro study | 6-Methylflavone is an activator of α 1 β 2 γ 2L and α 1 β 2 GABA A receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α 1 β 2 γ 2L and α 1 β 2 GABA A receptors (P<0.0001) at concentrations from 1 to 100 μ m. 6-Methylflavone (60 μ m) shifts the GABA dose-response curve to the left (n = 4, F = 16.38, P = 0.0004), decreasing the mean EC 50 at α 1 β 2 γ 2L GABA A receptors by 33±5.4%. |