6-Methoxy-o-toluidine

6-Methoxy-o-toluidine - Names and Identifiers

Name	2-methoxy-6-methylaniline
Synonyms	6-METHYL-O-ANISIDINE 6-Methoxy-o-toluidine 6-Methoxy-2-methylaniline 2-METHOXY-6-METHYLANILINE 2-methoxy-6-methylaniline 2-Methyl-6-methoxyaniline 2-Methoxy-6-methylbenzenamine 2-Methoxy-6-methyl-phenylamine 2-Amino-1-methoxy-3-methylbenzene
CAS	50868-73-0
InChI	InChI=1/C8H11NO/c1-6-4-3-5-7(10-2)8(6)9/h3-5H,9H2,1-2H3
InChIKey	HKOJYPPTIPJZAZ-UHFFFAOYSA-N

6-Methoxy-o-toluidine - Physico-chemical Properties

Molecular Formula	C8H11NO
Molar Mass	137.18
Density	1.0630 (rough estimate)
Melting Point	26-29 °C (lit.)
Boling Point	62 °C/0.15 mmHg (lit.)
Flash Point	>230°F
Solubility	Chloroform (Slightly), Methanol (Sparingly)
Vapor Presure	0.00782mmHg at 25°C
Appearance	Solid
Color	Clear Brown Oil to Pale Red to Dark Red Low Melting
pKa	4.39±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.5647 (estimate)
MDL	MFCD00075455

6-Methoxy-o-toluidine - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

6-Methoxy-o-toluidine - Introduction

2-methoxy-6-methylaniline is an organic compound with the chemical formula C9H13NO. It has the appearance of a white to yellow crystalline solid.

Nature:
-melting point: about 50-52 degrees Celsius
-Boiling point: 260 degrees Celsius
-Density: approx. 1.02g/cm³
-Solubility: Soluble in organic solvents such as ether, acetone and chloroform, insoluble in water.

Use:
2-methoxy-6-methylaniline is commonly used as an intermediate in organic synthesis. It can be used to synthesize compounds such as pesticides, dyes and pharmaceuticals. In addition, it can also be used for synthetic raw materials, surfactants and catalysts.

Preparation Method:
2-methoxy-6-methylaniline can be synthesized by the reaction of methoxybenzene chloride and acetone. More specifically, 2-methoxyaniline is first reacted with hydrochloric acid to give methoxybenzene chloride, which is then heated with methylbenzylamine under alkaline conditions to give 2-methoxy-6-methylaniline.

Safety Information:
2-methoxy-6-methylaniline should be considered a toxic compound. Wear appropriate personal protective equipment to avoid direct contact with skin, mouth and eyes. Pay attention to avoid dust and steam during operation. In case of accidental contact, immediately rinse the affected area with clean water and seek medical help. When storing, keep it in a cool, dry and well-ventilated place.

Last Update：2024-04-09 20:52:54