6-Phenylisoindolin-1-one

6-Phenylisoindolin-1-one - Names and Identifiers

Name	1H-Isoindol-1-one, 2,3-dihydro-6-phenyl-
Synonyms	6-Phenylisoindolin-1-one 6-Phenyl-2,3-dihydro-1H-isoindol-1-one 1H-Isoindol-1-one, 2,3-dihydro-6-phenyl-
CAS	160450-16-8

6-Phenylisoindolin-1-one - Physico-chemical Properties

Molecular Formula	C14H11NO
Molar Mass	209.24
Density	1.186±0.06 g/cm3(Predicted)
Boling Point	485.7±45.0 °C(Predicted)
pKa	13.95±0.20(Predicted)
Storage Condition	2-8°C

6-Phenylisoindolin-1-one - Introduction

1H-Isoindol-1-one, 2,3-dihydro-6-phenyl-, abbreviated as BDIK, is an organic compound. Its molecular formula is C14H11NO and its relative molecular mass is 209.25. The following is a description of the nature, use, formulation and safety information of BDIK:

1. Nature:
-Appearance: BDIK is a solid with yellow crystals.
-Melting point: The melting point of BDIK is 190-194 degrees Celsius.
-Solubility: BDIK soluble in organic solvents such as ethanol, methanol and dichloromethane, slightly soluble in ether solvents.

2. Use:
-Drug research: BDIK is an important compound, often used as a prodrug or intermediate in drug research.
-Anti-cancer research: BDIK has certain application potential in anti-cancer research and may have the effect of inhibiting tumor growth.
-Other uses: BDIK can also be used as catalysts and reagents in organic synthesis.

3. Preparation method:
-synthesis method one: BDIK can be obtained by reduction reaction of benzisoindolone with Phenylboronic acid or phenol.
-Synthesis Method 2: BDIK can also be obtained by palladium-catalyzed coupling reaction of Phenylboronic acid and 2-aminophenol.

4. Safety Information:
- BDIK is less toxic and dangerous, but care should still be taken to follow laboratory safety procedures.
-When contacting BDIK, avoid direct skin contact and inhalation of its dust.
-When storing and handling BDIK, avoid contact with oxidants and strong acids.

Last Update：2024-04-09 02:00:42