6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile

6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile - Names and Identifiers

Name	4-Amino-2-mercaptopyrimidine-5-carbonitrile
Synonyms	4-Amino-2-sulfanyl-5-pyrimidinecarbonitrile 4-AMINO-2-MERCAPTOPYRIMIDINE-5-CARBONITRILE 4-AMino-2-sulfanylpyriMidine-5-carbonitrile 4-Amino-2-mercaptopyrimidine-5-carbonitrile 6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile 6-Amino-1,2-dihydro-2-thioxo-5-pyrimidinecarbonitrile 6-amino-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile 5-PyriMidinecarbonitrile, 6-aMino-1,2-dihydro-2-thioxo-
CAS	16462-26-3
InChI	InChI=1/C5H4N4S/c6-1-3-2-8-5(10)9-4(3)7/h2H,(H3,7,8,9,10)

6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile - Physico-chemical Properties

Molecular Formula	C5H4N4S
Molar Mass	152.18
Density	1.58g/cm³
Boling Point	330°C at 760 mmHg
Flash Point	153.4°C
Vapor Presure	0.000172mmHg at 25°C
Refractive Index	1.78

6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3439
HS Code	29335990

6-amino-2-sulfanylidene-1H-pyrimidine-5-carbonitrile - Introduction

It is an organic compound (abbreviated as AMINOMETHYLTHIO-AMINOPYRIMIDINE). The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White or almost white crystal or crystalline powder.
-Molecular formula: C6H8N4S
-Molecular weight: 168.22g/mol
-Solubility: Soluble in water and ethanol.

Use:
-is an important intermediate compound that is widely used in the pharmaceutical industry to synthesize a variety of drugs.
-It can be used to synthesize antiviral drugs, anticancer drugs and immunomodulators, etc.

Method:
-It can be synthesized by the following steps:
1. A thioglycolic acid ester and aminopyrimidine are subjected to a condensation reaction in the presence of a carbonate associate catalyst to obtain 2-mercapto-4-aminopyrimidine.
2. 2-mercapto-4-aminopyrimidine reacts with formaldehyde under acidic conditions to obtain 2-mercapto-4-aminopyrimidine -5-carbaldehyde.
3. Finally, 2-mercapto -4-aminopyrimidine -5-formaldehyde is reacted with cyanamide to generate pyridine.

Safety Information:
-is a chemical that requires attention to safe operation.
-When using or handling the compound, wear appropriate personal protective equipment, such as protective glasses and gloves.
-Avoid contact with skin, eyes and respiratory tract, and ensure that the operation is carried out in a well-ventilated environment.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids and strong bases to avoid hazardous substances or hazardous reactions.
-If taken by mistake or inhaled, seek medical attention immediately and bring the packaging container or label.

Last Update：2024-04-09 21:00:56