6-amino-5-methylpyridine-3-carbonitrile

6-amino-5-methylpyridine-3-carbonitrile - Names and Identifiers

Name	6-AMINO-5-METHYLNICOTINONITRILE
Synonyms	BUTTPARK 8811-38 6-chloroquinazolin-2-amine 2-AMINO-5-CYANO-3-PICOLINE 6-AMINO-5-METHYLNICOTINONITRILE 5-Cyano-2-amino-3-methylpyridine 3-Pyridinecarbonitrile,6-amino-5-methyl 6-amino-5-methylpyridine-3-carbonitrile 6-Amino-5-methylpyridine-3-carbonitrile 3-Pyridinecarbonitrile,6-amino-5-methyl-(9CI)
CAS	183428-91-3
EINECS	214-589-6
InChI	InChI=1/C8H6ClN3/c9-6-1-2-7-5(3-6)4-11-8(10)12-7/h1-4H,(H2,10,11,12)

6-amino-5-methylpyridine-3-carbonitrile - Physico-chemical Properties

Molecular Formula	C7H7N3
Molar Mass	133.15
Density	1.445g/cm³
Boling Point	403.4°C at 760 mmHg
Flash Point	197.7°C
Vapor Presure	1.02E-06mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.726

6-amino-5-methylpyridine-3-carbonitrile - Risk and Safety

Risk Codes	41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S24/25 - Avoid contact with skin and eyes.
HS Code	29333990

6-amino-5-methylpyridine-3-carbonitrile - Introduction

It is an organic compound with the formula C8H11N3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid.
-Solubility: It is insoluble in water, but soluble in organic solvents such as ethanol and dichloromethane.
-Melting point: Its melting point is about 145-150 degrees Celsius.
-Stability: It is a stable compound.

Use: -Can be used as synthetic active pesticides, pharmaceutical intermediates and Organic Synthesis Reagents.
-it can be used in the field of medicine for the synthesis of antiviral drugs, anti-tumor drugs.
-It can also be used for synthetic dyes, flavors, rubber additives, etc.

Method:
The preparation can be done through the following steps:
1. Pyridine reacts with ethane nitrile to generate 2-ethyl-5-aminopyridine.
2. Reacting 2-ethyl-5-aminopyridine with methyl iodide to generate 5-methyl -6-aminopyridine.
3. Finally, the generated 5-methyl-aminopyridine reacts with the hydrocyanic acid in chloroform to generate 6-Fluorene.

Safety Information:
-The specific toxicity data may be limited, but it should be noted that it is an organic synthetic reagent with certain toxicity and irritation.
-During operation, necessary safety measures should be taken, including wearing protective gloves, goggles and other personal protective equipment.
-Avoid inhalation, ingestion or contact with skin.
-In case of accidental contact or discomfort, seek medical attention immediately.

Last Update：2024-04-09 21:00:56