6-aminopyridine-3-carboxylate
Ethyl 6-aminonicotinate
CAS: 39658-41-8
Molecular Formula: C8H10N2O2
6-aminopyridine-3-carboxylate - Names and Identifiers
6-aminopyridine-3-carboxylate - Physico-chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molar Mass | 166.18 |
| Density | 1.192±0.06 g/cm3(Predicted) |
| Melting Point | 145-147 |
| Boling Point | 314.7±22.0 °C(Predicted) |
| Flash Point | 144.1°C |
| Vapor Presure | 0.000457mmHg at 25°C |
| pKa | 4.88±0.13(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| MDL | MFCD04972544 |
6-aminopyridine-3-carboxylate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Note | Irritant |
6-aminopyridine-3-carboxylate - Introduction
Ethyl 6-aminonicotinate, also known as ethylated 6-aminonicotinate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: White or yellowish crystalline or powdery solid.
-Chemical formula: C9H10N2O2
-Molecular weight: 178.19g/mol
-Solubility: It has good solubility, soluble in most organic solvents such as ethanol and dimethylformamide, and slightly soluble in water.
2. use:
-Pharmaceutical field: Ethyl 6-aminonicotinate can be used as a synthetic drug intermediate for the preparation of some biologically active compounds, such as anti-inflammatory drugs and anti-tumor drugs.
-Scientific research field: Ethyl 6-aminonicotinate is also commonly used in organic synthetic chemistry research as an important raw material and reagent.
3. Preparation method:
- Ethyl 6-aminonicotinate can be prepared by reacting 6-aminonicotinate with acetic anhydride or ethyl acetate. The reaction may be carried out in a solvent with the addition of a desired catalyst such as metaphosphoric acid or zinc chloride. The reaction temperature is generally carried out at room temperature.
-After preparation, the pure product can be obtained by crystallization purification.
4. Safety Information:
- Ethyl 6-aminonicotinate is generally considered to have less impact on the human body under normal conditions of use. However, as a chemical substance, it is still necessary to pay attention to safe operation.
-When using, wear appropriate protective gloves and glasses to avoid skin contact and inhalation.
-Avoid reacting with strong oxidants or strong acids to avoid dangerous substances or fire.
-Store away from fire and heat sources, and store in a sealed container.
1. nature:
-Appearance: White or yellowish crystalline or powdery solid.
-Chemical formula: C9H10N2O2
-Molecular weight: 178.19g/mol
-Solubility: It has good solubility, soluble in most organic solvents such as ethanol and dimethylformamide, and slightly soluble in water.
2. use:
-Pharmaceutical field: Ethyl 6-aminonicotinate can be used as a synthetic drug intermediate for the preparation of some biologically active compounds, such as anti-inflammatory drugs and anti-tumor drugs.
-Scientific research field: Ethyl 6-aminonicotinate is also commonly used in organic synthetic chemistry research as an important raw material and reagent.
3. Preparation method:
- Ethyl 6-aminonicotinate can be prepared by reacting 6-aminonicotinate with acetic anhydride or ethyl acetate. The reaction may be carried out in a solvent with the addition of a desired catalyst such as metaphosphoric acid or zinc chloride. The reaction temperature is generally carried out at room temperature.
-After preparation, the pure product can be obtained by crystallization purification.
4. Safety Information:
- Ethyl 6-aminonicotinate is generally considered to have less impact on the human body under normal conditions of use. However, as a chemical substance, it is still necessary to pay attention to safe operation.
-When using, wear appropriate protective gloves and glasses to avoid skin contact and inhalation.
-Avoid reacting with strong oxidants or strong acids to avoid dangerous substances or fire.
-Store away from fire and heat sources, and store in a sealed container.
Last Update：2024-04-09 02:00:46
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Product Name: Ethyl 6-Aminonicotinate Visit Supplier Webpage Request for quotation
CAS: 39658-41-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 39658-41-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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