6-bromo-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-one - Names and Identifiers
| Name | 6-bromo-1,3,3-trimethylindolin-2-one
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| Synonyms | 6-bromo-1,3,3-trimethylindol-2-one
6-bromo-1,3,3-trimethylindolin-2-one
6-Bromo-1,3,3-trimethyl-1,3-dihydro-indol-2-one
6-bromo-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-one
2H-Indol-2-one, 6-bromo-1,3-dihydro-1,3,3-trimethyl-
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| CAS | 1190861-69-8
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6-bromo-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-one - Physico-chemical Properties
6-bromo-1,3,3-trimethyl-2,3-dihydro-1H-indol-2-one - Introduction
6-bromo-1,3,3-trimethylindolin-2-one is an organic compound with the chemical formula C12H14BrNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular weight: 279.15g/mol
-Melting point: 120-123 ° C
-Boiling point: 392.6 ° C (predicted)
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, acetone and dichloromethane
-is a compound with an indoline ring and a ketone group, with high chemical stability
Use:
- 6-bromo-1, 3,3-trimethyllindolin-2-one can be used as an intermediate for fluorescent dyes
-Can also be used to synthesize organic materials with photoelectric, optical and electrical properties
-Can be used as a reagent or catalyst in organic synthesis reactions
Method:
- 6-bromo-1,3,3-trimethylindolin-2-one can be prepared by the following steps:
1. Indoline is reacted with bromoethanone under alkaline conditions to obtain 6-bromoindoline.
2.6-bromoindoline reacts with methyl iodide to generate 6-bromo -1,3,3-trimethyl indoline.
3. Finally, 6-bromo-1,3,3-trimethylindolin was reacted with a ketone-forming reagent to prepare 6-bromo-1,3,3-trimethylindolin-2-one.
Safety Information:
- 6-bromo-1, 3,3-trimethindolin-2-one has limited safety information, and general laboratory safety practices need to be followed when using it.
-Because the compound is an organic bromide, it may have certain toxicity to the human body and the environment. Direct contact with the skin and inhalation of its dust or vapor should be avoided.
-Wear gloves and protective glasses during use, and ensure that you operate in a well-ventilated place.
-In case of contact, rinse the affected area immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15