6-bromo-1H-isobenzofuran-1-one

6-bromo-1H-isobenzofuran-1-one - Names and Identifiers

Name	6-BROMO-3 H-ISOBENZOFURAN-1-ONE
Synonyms	6-Bromophthalide Roxadustat Impurity 12 6-bromo-1(3H)-isobenzofuanone 6-Bromo-3H-isobenzofuran-1-one 6-bromo-1H-isobenzofuran-1-one 6-bromo-2-benzofuran-1(3H)-one 6-Bromo-2-benzofuran-1(3H)-one 6-BROMO-3 H-ISOBENZOFURAN-1-ONE 1(3H)-Isobenzofuranone, 6-bromo- 1(3H)-Isobenzofuranone, 6-broMo- 6-broMo-1,3-dihydro-2-benzofuran-1-one
CAS	19477-73-7
InChI	InChI=1/C8H5BrO2/c9-6-2-1-5-4-11-8(10)7(5)3-6/h1-3H,4H2

6-bromo-1H-isobenzofuran-1-one - Physico-chemical Properties

Molecular Formula	C8H5BrO2
Molar Mass	213.03
Density	1.742±0.06 g/cm3(Predicted)
Melting Point	99.5 °C
Boling Point	362.4±42.0 °C(Predicted)
Flash Point	172.998°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	2-8°C
Refractive Index	1.625

6-bromo-1H-isobenzofuran-1-one - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29322090

6-bromo-1H-isobenzofuran-1-one - Introduction

6-BROMO-3 H-ISOBENZOFURAN-1-ONE is an organic compound with the chemical formula C12H7BrO. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 6-BROMO-3 H-ISOBENZOFURAN-1-ONE is a white to yellowish solid.
-Melting point: Its melting point is about 120-124 ° C.
-Solubility: It is soluble in organic solvents, such as ethanol, ether and dichloromethane.

Use:
- 6-BROMO-3 H-ISOBENZOFURAN-1-ONE is often used as an intermediate in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs, pesticides and dyes.

Method:
-A commonly used preparation method is obtained by the reaction of bromobenzofuran. First, benzofuran is reacted with bromine in an appropriate solvent, and then purified by crystallization or column chromatography to obtain the target product.

Safety Information:
- 6-BROMO-3 H-ISOBENZOFURAN-1-ONE should pay attention to protective measures during operation, such as wearing protective glasses and gloves, and ensure that they are operated in a well-ventilated place.
-During storage and handling, keep away from fire and oxidizing agents and keep them sealed.
-Due to its chemical properties that may pose risks to health, it is recommended to follow relevant safe operating procedures when using it, and use personal protective equipment according to the situation.

Last Update：2024-04-09 21:01:54