6-bromo-4-methylpyridine-3-carbonitrile
2-BROMO-5-CYANO-4-PICOLINE
CAS: 1003711-35-0
Molecular Formula: C7H5BrN2
6-bromo-4-methylpyridine-3-carbonitrile - Names and Identifiers
6-bromo-4-methylpyridine-3-carbonitrile - Physico-chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molar Mass | 197.03 |
| Density | 1.61 |
| Boling Point | 288℃ |
| Flash Point | 128℃ |
| pKa | -2.00±0.18(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
6-bromo-4-methylpyridine-3-carbonitrile - Reference Information
| introduction | 6-bromo -4-methylpyridine -3-nitrile is a pharmaceutical intermediate, and it has been reported in the literature that it can be used to prepare PDE4 inhibitors and ROMK channel inhibitors. |
| Application | 6-bromo-4-methylpyridin-3-nitrile can be used as a substitute for the inhibitor of ROMK channel activity The nitrogen-containing heterocyclic compound. Multiple lines of evidence indicate that inhibition of ROMK channel activity causes urinary sodium excretion, diuresis, and decreased blood pressure. Thus, ROMK inhibition may provide novel mechanisms for blood pressure regulation and diuresis in patients with hypertension, congestive heart failure, or any other edematous disease condition. |
Last Update：2024-04-09 01:59:59
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CAS: 1003711-35-0
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CAS: 1003711-35-0
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