6-bromo-N-methyl-3-pyridazinamine
6-bromo-N-methyl-3-pyridazinamine
CAS: 1208657-07-1
Molecular Formula: C5H6BrN3
6-bromo-N-methyl-3-pyridazinamine - Names and Identifiers
| Name | 6-bromo-N-methyl-3-pyridazinamine |
| Synonyms | 6-bromo-N-methyl-3-pyridazinamine 6-BROMO-N-methylpyridazin-3-amine 3-Pyridazinamine, 6-bromo-N-methyl- |
| CAS | 1208657-07-1 |
6-bromo-N-methyl-3-pyridazinamine - Physico-chemical Properties
| Molecular Formula | C5H6BrN3 |
| Molar Mass | 188.03 |
| Density | 1.686±0.06 g/cm3(Predicted) |
| Boling Point | 349.6±27.0 °C(Predicted) |
| pKa | 4.36±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
6-bromo-N-methyl-3-pyridazinamine - Introduction
It is an organic compound with the chemical formula C6H7BrN4.
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in some common organic solvents, such as ethanol and dimethylformamide
-Melting point: about 155-159 ℃
-Stability: relatively stable at room temperature, but may decompose when heated or exposed to sunlight
Use:
-is an intermediate compound, usually used to synthesize other organic compounds, such as drugs and pesticides
-It can be used in the synthesis of antibacterial and anti-inflammatory drugs in the field of medicine
Preparation Method:
It can be synthesized by the following steps:
1. Synthesis of 3-bromo-6-nitropyridazine (6-bromo-3-nitropyridazine). The nitro group was introduced in 3-bromopyridazine by a nitration reaction.
2. Reduction of 3-bromo-6-nitropyridazine, usually using sodium nitrite (NaNO2) and dilute acid for reaction, to obtain 3-bromo-6-aminopyridazine (6-bromo-3-aminopyridazine).
3. Through the methylation reaction, the methyl group is introduced into 3-bromo-6-aminopyridazine, and the methyl group is obtained.
Safety Information:
-is a chemical, should pay attention to safe operation, and follow the relevant safety procedures.
-It may be irritating to the eyes, skin and respiratory system, avoid contact.
-Avoid inhaling dust, avoid skin contact, and avoid swallowing when handling or using.
-When storing, it should be stored in a cool, dry, well-ventilated place, away from fire and flammable materials.
Nature:
-Appearance: Colorless crystalline solid
-Solubility: Soluble in some common organic solvents, such as ethanol and dimethylformamide
-Melting point: about 155-159 ℃
-Stability: relatively stable at room temperature, but may decompose when heated or exposed to sunlight
Use:
-is an intermediate compound, usually used to synthesize other organic compounds, such as drugs and pesticides
-It can be used in the synthesis of antibacterial and anti-inflammatory drugs in the field of medicine
Preparation Method:
It can be synthesized by the following steps:
1. Synthesis of 3-bromo-6-nitropyridazine (6-bromo-3-nitropyridazine). The nitro group was introduced in 3-bromopyridazine by a nitration reaction.
2. Reduction of 3-bromo-6-nitropyridazine, usually using sodium nitrite (NaNO2) and dilute acid for reaction, to obtain 3-bromo-6-aminopyridazine (6-bromo-3-aminopyridazine).
3. Through the methylation reaction, the methyl group is introduced into 3-bromo-6-aminopyridazine, and the methyl group is obtained.
Safety Information:
-is a chemical, should pay attention to safe operation, and follow the relevant safety procedures.
-It may be irritating to the eyes, skin and respiratory system, avoid contact.
-Avoid inhaling dust, avoid skin contact, and avoid swallowing when handling or using.
-When storing, it should be stored in a cool, dry, well-ventilated place, away from fire and flammable materials.
Last Update：2024-04-09 02:00:49
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