6-bromoisoindolin-1-one - Names and Identifiers
Name | 6-bromoisoindolin-1-one
|
Synonyms | 6-bromoisoindolin-1-one 6-BroMo-2,3-dihydro-isoindol-1-one 6-Bromo-2,3-dihydroisoindolin-1-one 6-broMo-2,3-dihydro-1H-isoindol-1-one 6-bromo-2,3-dihydro-1H-isoindol-1-one 1H-Isoindol-1-one, 6-broMo-2,3-dihydro- 1H-Isoindol-1-one, 6-bromo-2,3-dihydro- 1-Piperidinecarboxylicacid,4-(2-bromoethyl)-,1,4-dimethylethylester
|
CAS | 675109-26-9
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InChI | InChI=1/C8H6BrNO/c9-6-2-1-5-4-10-8(11)7(5)3-6/h1-3H,4H2,(H,10,11) |
6-bromoisoindolin-1-one - Physico-chemical Properties
Molecular Formula | C8H6BrNO
|
Molar Mass | 212.04 |
Density | 1.666±0.06 g/cm3(Predicted) |
Boling Point | 431.7±45.0 °C(Predicted) |
Flash Point | 214.881°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 13.87±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.625 |
6-bromoisoindolin-1-one - Introduction
6-bromoisoindolin-1-one is an organic compound with the chemical formula C8H5BrNO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 6-bromoisoindolin-1-one is white or light yellow crystalline powder.
-Melting point: about 156-158°C.
-Solubility: Soluble in organic solvents such as chloroform, ethanol, dichloromethane and ether.
Use:
6-bromoisoindolin-1-one has important application value in drug synthesis. It is a synthetic intermediate for many bioactive molecules. The compound can be used as a raw material in the fields of pharmaceuticals, dyes and pesticides.
Preparation Method:
6-bromoisoindolin-1-one is usually synthesized by the following steps:
1. reacting isoindolone with bromine in alcohol or chlorinated hydrocarbon solvent;
2. treating the reactant in an acidic solution to form the target product;
3. 6-bromoisoindolin-1-one was obtained by crystallization and purification steps.
Safety Information:
- 6-bromoisoindolin-1-one is an organic compound that has certain safety risks and needs to be used and handled correctly in the laboratory.
-When using this compound, you should wear appropriate personal protective equipment, such as goggles and gloves.
-Avoid contact with skin, eyes and clothing, and avoid inhaling its powder or gas.
-Keep it away from ignition and flammable materials during storage and handling.
-Follow proper laboratory safety practices and waste disposal measures when using or handling the compound.
Please note that the above information is for reference only. When actually using the compound, please strictly follow the guidelines and requirements of relevant chemical experiments.
Last Update:2024-04-09 15:17:59