6-chloro-4-iodopyridine-3-carbonitrile

6-chloro-4-iodopyridine-3-carbonitrile - Names and Identifiers

Name	6-chloro-4-iodopyridine-3-carbonitrile
Synonyms	2-Chloro-5-cyano-4-iodopyridine 6-chloro-4-iodopyridine-3-carbonitrile 6-Chloro-4-iodo-3-pyridinecarbonitrile 3-Pyridinecarbonitrile, 6-chloro-4-iodo-
CAS	1061357-83-2

6-chloro-4-iodopyridine-3-carbonitrile - Physico-chemical Properties

Molecular Formula	C6H2ClIN2
Molar Mass	264.45
Density	2.13±0.1 g/cm3(Predicted)
Boling Point	329.3±42.0 °C(Predicted)
pKa	-3.73±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

6-chloro-4-iodopyridine-3-carbonitrile - Introduction

6-Chloro-4-iodo-3-nitrilopyridine (CIP) is an organic compound with the chemical formula C9H4ClIN2. The following is an introduction to some of the properties, uses, methods and safety information of CIP:

Nature:
-Appearance: colorless crystal or white powder
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dimethyl sulfoxide
-Melting point: about 152-153°C
-Stability: CIP is a stable compound, which is not easy to decompose under conventional experimental conditions

Use:
-Active intermediate: CIP can be used as an active intermediate in organic synthesis for the synthesis of organic compounds, such as pyridine compounds, iodine compounds, etc.

Preparation Method:
CIP can be synthesized by the following steps:
1. Add pyronitrosamine in iodobenzene and react to synthesize 3-chloro-4-iodopyridine
2. Cyanation of 3-chloro-4-iodopyridine to obtain 6-chloro-4-iodo-3-carbonylpyridine

Safety Information:
- CIP is an organic compound with certain toxicity and requires attention to safe operation.
-in the use of CIP, should follow the laboratory safety procedures, wear protective glasses, gloves, clothing and other personal protective equipment.
-Avoid contact with skin and eyes, and avoid inhaling its dust or vapor.
-Pay attention to fire prevention and static electricity accumulation during storage and handling, and avoid contact with oxidants.

Last Update：2024-04-10 22:29:15