6-chloro-9-pentofuranosyl-9H-purin-2-amine
2-Amino-6-chloropurine-9-riboside
CAS: 2004-07-1
Molecular Formula: C10H12ClN5O4
6-chloro-9-pentofuranosyl-9H-purin-2-amine - Names and Identifiers
| Name | 2-Amino-6-chloropurine-9-riboside |
| Synonyms | 6-CHLOROGUANOSINE 6-Chloroguanosine 6-CHLOROADENOSINE 6-CHLOROGUANINE RIBOSIDE 2-AMINO-6-CHLOROPURINE RIBOSIDE 2-Amino-6-chloropurine-9-riboside 2-AMINO-6-CHLOROPURINE-9-RIBOSIDE 2-AMINO-6-CHLOROPURINE-9-BETA-D-RIBOSIDE 6-chloro-9-pentofuranosyl-9H-purin-2-amine 2-AMINO-6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE 6-chloro-9-beta-D-ribofuranosyl-9H-purin-2-amine 6-chloro-9-(beta-D-ribofuranosyl)-9H-purin-2-amine |
| CAS | 2004-07-1 |
| EINECS | 217-905-3 |
| InChI | InChI=1/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15) |
| InChIKey | TXWHPSZYRUHEGT-ACJOCUEISA-N |
6-chloro-9-pentofuranosyl-9H-purin-2-amine - Physico-chemical Properties
| Molecular Formula | C10H12ClN5O4 |
| Molar Mass | 301.69 |
| Density | 1.8359 (rough estimate) |
| Melting Point | 165-167°C (dec.)(lit.) |
| Boling Point | 729.9±70.0 °C(Predicted) |
| Flash Point | 395.2°C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 2.3E-22mmHg at 25°C |
| Appearance | Colorless crystal |
| Color | White to Off-white |
| pKa | 13.05±0.70(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | -38 ° (C=0.1, H2O) |
| MDL | MFCD00005735 |
6-chloro-9-pentofuranosyl-9H-purin-2-amine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Hazard Note | Irritant |
6-chloro-9-pentofuranosyl-9H-purin-2-amine - Introduction
It is a kind of nucleoside compound containing chlorine atom, chemical formula is C10H12ClN5O4. It is a derivative of adenosine and has certain physiological activity in vivo.
Regarding the nature of, it is a white crystalline solid, soluble in water and alcohol. Its melting point is about 214-218 degrees Celsius. It has antiviral and antitumor activity and can be used as a raw material for drug research and pharmaceutical applications.
It is mainly used in the research and development of antiviral and antitumor drugs. It has strong anti-HSV and anti-breast cancer cell activity. In the medical field, calcium can be used to inhibit viral replication and cell proliferation, and therefore may play a role in antiviral and antitumor therapy.
The method of preparation is usually based on the synthesis of adenosine. The specific operation is to react adenosine with thionyl chloride, and introduce chlorine atoms under alkaline conditions, thus generating calcium.
Regarding safety information, the specific toxicity of calcium is related to the dose and route of use. It may cause certain toxicity and irritation to the human body, so it is necessary to follow relevant safety operating procedures and pay attention to personal protective measures when using it. When using and storing, keep it away from fire source and open flame, avoid contact with skin and eyes, and avoid inhaling dust or mist. In addition, it should be placed in a cool, dry and well-ventilated place, away from acids, oxidants and food. In case of inadvertent inhalation, contact or ingestion, seek medical assistance as soon as possible.
Regarding the nature of, it is a white crystalline solid, soluble in water and alcohol. Its melting point is about 214-218 degrees Celsius. It has antiviral and antitumor activity and can be used as a raw material for drug research and pharmaceutical applications.
It is mainly used in the research and development of antiviral and antitumor drugs. It has strong anti-HSV and anti-breast cancer cell activity. In the medical field, calcium can be used to inhibit viral replication and cell proliferation, and therefore may play a role in antiviral and antitumor therapy.
The method of preparation is usually based on the synthesis of adenosine. The specific operation is to react adenosine with thionyl chloride, and introduce chlorine atoms under alkaline conditions, thus generating calcium.
Regarding safety information, the specific toxicity of calcium is related to the dose and route of use. It may cause certain toxicity and irritation to the human body, so it is necessary to follow relevant safety operating procedures and pay attention to personal protective measures when using it. When using and storing, keep it away from fire source and open flame, avoid contact with skin and eyes, and avoid inhaling dust or mist. In addition, it should be placed in a cool, dry and well-ventilated place, away from acids, oxidants and food. In case of inadvertent inhalation, contact or ingestion, seek medical assistance as soon as possible.
Last Update：2024-04-09 21:54:55
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CAS: 2004-07-1
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Spot supply
Product Name: Regadenoson Impurity 40 Visit Supplier Webpage Request for quotationCAS: 2004-07-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: 2-Amino-6-chloropurine riboside Visit Supplier Webpage Request for quotationCAS: 2004-07-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 6-Chloroguanine riboside Request for quotation
CAS: 2004-07-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
CAS: 2004-07-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: 13651600618
WhatsApp: +8613651600618
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