6-difluoro-4-hydroxybenzaldehyde

6-difluoro-4-hydroxybenzaldehyde - Names and Identifiers

Name	2,6-Difluoro-4-hydroxybenzaldehyde
Synonyms	102286 VHR DQ BF FF 3,5-Difluoro-4-formylphenol 6-difluoro-4-hydroxybenzaldehyde 2,6-Difluor-4-hydroxybenzaldehyd 2,6-Difluoro-4-hydroxybenzaldehyde 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE Benzaldehyde, 2,6-difluoro-4-hydroxy- Benzaldehyde, 2,6-difluoro-4-hydroxy- (9CI) 2,6-difluoro-4-hydroxybenzaldehyde2,6-difluoro-4-hydroxybenzaldehyde
CAS	532967-21-8
InChI	InChI=1/C7H4F2O2/c8-6-1-4(11)2-7(9)5(6)3-10/h1-3,11H

6-difluoro-4-hydroxybenzaldehyde - Physico-chemical Properties

Molecular Formula	C7H4F2O2
Molar Mass	158.1
Density	1.464±0.06 g/cm3(Predicted)
Melting Point	179-182℃
Boling Point	252.6±35.0 °C(Predicted)
Flash Point	106.5°C
Vapor Presure	0.0121mmHg at 25°C
Appearance	Crystalline powder
pKa	5.80±0.23(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.559
MDL	MFCD07772042

6-difluoro-4-hydroxybenzaldehyde - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20 - Harmful by inhalation R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
HS Code	29124990
Hazard Note	Irritant

6-difluoro-4-hydroxybenzaldehyde - Introduction

The chemical formula is C7H4F2O2.

Nature:
-Appearance: Colorless to light yellow crystals or powdery substances.
-Melting point: about 82-85°C.
-Boiling point: about 227-228 ℃.
-Density: about 1.49-1.52g/cm3.
-Solubility: Soluble in many organic solvents, such as chloroform, dichloromethane and ethanol.

Use:
- 2, can be used as an intermediate in organic synthesis, widely used in the synthesis of other compounds.
-This compound is commonly used in the preparation of heterocyclic compounds containing hydroxyl groups and fluorine atoms, such as amino acids, drugs and dyes.

Preparation Method:
- 2, usually prepared by hydroxylation of p-benzylidene difluoro compounds.
-The specific preparation method can be obtained by reacting hydrogen peroxide and aldehydes, or by reacting sodium acetylacetonate with hydrogen fluoride.

Safety Information:
- 2, it is usually stable under normal use conditions.
-This compound should be kept away from fire and oxidizing agents.
-Wear appropriate personal protective equipment, such as lab gloves and protective glasses, during operation or contact.
-Seek immediate medical assistance if swallowed or in contact with skin or eyes.
-Detailed safety information can be found in the relevant Chemical Safety Data Sheet (MSDS).

Last Update：2024-04-09 02:00:46